研究动态
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全球性的营养支持实践分析——针对行腹膜恶性肿瘤细胞减灭手术和高温腹腔灌注化疗的患者

A global analysis of nutrition support practices in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal malignancy.

发表日期:2023 Oct
作者: Lauren Reece, Brendan Moran, Suzie Ferrie, Nabila Ansari, Cherry Koh, Margaret Allman-Farinelli, Sharon Carey
来源: Best Pract Res Cl Ob

摘要:

手术围手术期的营养护理已被确认为细胞减灭手术(Cytoreductive surgery,CRS)和腹腔热疗化学治疗(Hyperthermic intraperitoneal chemotherapy,HIPEC)患者管理中的重要因素。然而,目前尚无关于这类患者的最佳营养管理实践的公开共识。本研究的目的是调查全球进行CRS和HIPEC治疗腹膜恶性肿瘤患者的国际医疗机构的现行营养护理实践。我们开发了一份在线调查问卷,并发送给有经验的CRS和HIPEC治疗中心。调查问题涵盖了临床医生和机构的基本信息、正式的营养护理途径、术前营养护理、术后营养支持和出院后的营养随访。共联系了82个中心,收到42份回复。参与者来自20个不同国家,主要为营养师(71%)。营养评估经常进行(术前52%,术后86%),大多数中心使用了经过验证的营养筛查或评估工具(79%)。关于肠内营养、肠外营养和术后快速康复等手术围手术期的营养支持,在不同中心之间存在很大的差异。欧洲中心的例行肠外和肠内营养使用率明显高于其他地区(p =0.028)。营养护理在全球范围内已经成为细胞减灭手术和腹腔热疗化学治疗患者综合管理中至关重要的一环,然而实践中存在差异。研究结果凸显了共同研究营养在结果中的作用,并确定最适当的营养支持方法,以改善这类高风险患者的临床预后的独特机会。版权归 Crown © 2023 所有,由 Elsevier Ltd 发表。保留所有权利。
Perioperative nutritional care has been identified as an important factor in the management of patients undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Nevertheless, there is no published consensus on best practice for nutritional management specific to this patient group. The purpose of this study was to identify the current nutrition care practices among international centres performing CRS and HIPEC for patients with peritoneal malignancy.An online survey was developed and sent to experienced CRS and HIPEC centres. The survey questions covered clinician and institution demographics, formal nutrition care pathways, pre-operative nutrition care, post-operative nutrition support and post-discharge nutritional follow-up.Eighty-two centres were contacted, and 42 responses were received. Respondents were from 20 different countries and were mostly dietitians (71%). Nutrition assessments were frequently completed (52% pre-operatively and 86% post-operatively) and most centres used a validated nutrition screening or assessment tool (79%). Perioperative nutrition support with respect to the use of enteral nutrition, parenteral nutrition and enhanced recovery after surgery varied widely between centres. The use of routine parenteral and enteral nutrition was significantly higher in Europe compared with other locations (p = 0.028).Nutrition care is pivotal and has been positively integrated into the complex management of patients undergoing CRS and HIPEC globally, however variation in practice is evident. The findings highlight a unique opportunity to collaboratively investigate the role nutrition plays in determining outcomes and to identify the most appropriate nutrition support methods to achieve improved clinical outcomes for these high-risk patients.Crown Copyright © 2023. Published by Elsevier Ltd. All rights reserved.