研究动态
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尼泊尔男性COVID-19感染后症状的频率、强度和自然历史的连续系列研究。

A Consecutive Series Study of the Frequencies, Intensities, and Natural History of Symptoms Following COVID-19 Infection in Nepali Men.

发表日期:2023 Sep 08
作者: Deepak Sundar Shrestha, Arafat Mahamood Rahat, Parama Sridevi, Bimal Sharma Chalise, Sagar Kumar Rajbhandari, Anup Bastola, Parmananda Bhandari, Sheikh Iqbal Ahamed, Richard R Love
来源: MEDICINE & SCIENCE IN SPORTS & EXERCISE

摘要:

在尼泊尔,大约有一百万人中,其中三分之二为男性,新冠病毒检测呈阳性。关于这种感染的康复情况没有被描述。在加德满都的一个主要检测机构中,我们尝试与接受核酸检测后三到四个月的男性进行联系。如果被联系到的男性同意并报告他们没有完全康复,我们即向他们询问关于23种症状的存在和程度。在连续2043名核酸检测呈阳性的男性中,我们成功联系到了1254名男性或其家庭成员。在我们的呼叫之前,有14名男性已经去世,还有两人报告患有癌症或结核病,因此得到了1238个个体。其中318人(25.7%)报告称他们还没有康复,其中311人的采访顺利进行。在诊断后中位数为3.5个月的时间里,216人(17.4%)报告疲劳, 153人(12.4%)报告疼痛,134人(10.8%)报告记忆困难,133人(10.7%)报告身体活动受限,114人(9.2%)报告呼吸急促,114人(9.2%)报告睡眠质量差。到了6个月和9个月时,分别有108人(8.7%)和55人(4.4%)还未康复。在这组接受核酸检测呈阳性的男性症状系列中,康复时间明显延长,与其他病毒感染相比。
In Nepal, approximately one million individuals, two-thirds men, have tested positive for COVID-19. The recovery picture from this infection is undescribed.At one major testing institution in Kathmandu, we attempted to contact men three-four months following documentation of a positive PCR Covid test. If the men contacted consented and reported that they had not completely recovered from their Covid infection, we then sought their answers about the presence and intensities of 23 symptoms.Of 2043 consecutive test-positive men, we successfully contacted 1254 men/or family members. 14 men had died before our calls, and two reported having cancer or tuberculosis, providing 1238 individuals. 318 (25.7%) reported that they were unrecovered and 311 of these men were successfully interviewed. At a median of 3.5 months from diagnosis, 216 (17.4%) men reported fatigue, 153 (12.4%) pain, 134 (10.8%) difficulty remembering, 133 (10.7%) reduced physical activity, 114 (9.2%) shortness of breath, and 114 (9.2%) poor sleep. By 6 and 9 months, 108 (8.7%) and 55 (4.4%) of men respectively were still unrecovered.In this PCR Covid test-positive series of symptomatic men, recovery was significantly prolonged compared with other viral illnesses.