癌症是现代世界的一个重要死因，它是一种隐匿的病理学，应该在早期诊断出来才能成功治疗。临床科学对开发具有最小侵入性和高效能区分肿瘤细胞和正常细胞的治疗干预措施特别感兴趣，因为它们可以提高患者的生存率。纳米颗粒是一种宝贵的资产，可用于开发此类诊断和治疗方式，因为它们尺寸非常小，表面可修饰，高度安全和稳定，并且可以以受控方式合成。迄今为止，不同的纳米颗粒已被纳入多种治疗方式，例如肿瘤靶向治疗、热疗、化疗和放疗。这篇综述文章旨在简要介绍纳米颗粒在基于热疗的癌症治疗中的研究和应用的最新进展。总结了最新的研究，强调了热化疗联合放疗发展的最新进展，以及纳米粒子在癌症治疗中应用所面临的挑战。本文分类为：治疗方法和药物发现 > 肿瘤疾病纳米医学。© 2023 Wiley periodicals LLC。

A pivotal cause of death in the modern world, cancer is an insidious pathology that should be diagnosed at an early stage for successful treatment. Development of therapeutic interventions with minimal invasiveness and high efficacy that can discriminate between tumor and normal cells is of particular interest to the clinical science, as they can enhance patient survival. Nanoparticles are an invaluable asset that can be adopted for development of such diagnostic and therapeutic modalities, since they come in very small sizes with modifiable surface, are highly safe and stable, and can be synthesized in a controlled fashion. To date, different nanoparticles have been incorporated into numerous modalities such as tumor-targeted therapy, thermal therapy, chemotherapy, and radiotherapy. This review article seeks to deliver a brief account of recent advances in research and application of nanoparticles in hyperthermia-based cancer therapies. The most recent investigations are summarized to highlight the latest advances in the development of combined thermo-chemo-radiotherapy, along with the challenges associated with the application of nanoparticles in cancer therapy. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease.© 2023 Wiley Periodicals LLC.