抗焦虑药会引起胰腺癌的焦虑。
Anxiolytics cause anxiety in pancreatic cancer.
发表日期：2023 Nov
作者：
Yang Chen, Anirban Maitra
来源：
Trends in Cancer
摘要：
苯二氮卓类药物 (BZD) 通常用于治疗胰腺癌患者。为了调查 BZD 与生存结果之间的相关性，Cornwell 等人最近进行了一项研究。发现劳拉西泮 (LOR) 与较差的生存率相关。机制研究表明，LOR 通过 GPR68 增加癌症相关成纤维细胞中白细胞介素 6 (IL6) 的表达。版权所有 © 2023 Elsevier Inc. 保留所有权利。
Benzodiazepines (BZDs) are commonly prescribed for pancreatic cancer patients. To investigate the correlation between BZDs and survival outcomes a recent study by Cornwell et al. found that lorazepam (LOR) correlates with poor survival. The mechanistic study shows that LOR increases interleukin 6 (IL6) expression in cancer-associated fibroblasts via GPR68.Copyright © 2023 Elsevier Inc. All rights reserved.