通过抑制 BCL2 增强树突状细胞。
Enhancing dendritic cells by inhibiting BCL2.
发表日期:2023 Sep 30
作者:
Christopher A G Booth, Andrew A Lane
来源:
Trends in Cancer
摘要:
树突状细胞通过将 T 细胞暴露于肿瘤相关抗原,在抗癌免疫中发挥重要作用。在最近的一项研究中,赵等人。研究表明,BCL2 抑制可提高树突状细胞向 T 细胞呈递抗原并激活其抗肿瘤细胞毒性的能力。版权所有 © 2023 Elsevier Inc. 保留所有权利。
Dendritic cells play an important role in anticancer immunity by exposing T cells to tumor-associated antigens. In a recent study, Zhao et al. show that BCL2 inhibition improves the ability of dendritic cells to present antigen to T cells and activate their antitumor cytotoxicity.Copyright © 2023 Elsevier Inc. All rights reserved.