与传统腹腔镜右半结肠切除术相比，机器人右半结肠切除术治疗右结肠癌的短期结果已得到广泛研究。然而，除了单中心回顾性研究外，这两种方法的长期肿瘤学结果尚未得到调查。因此，本荟萃分析旨在研究机器人右半结肠切除术与腹腔镜右半结肠切除术治疗右结肠癌的长期肿瘤学结果。我们检索了 PubMed、EMBASE 和 Cochrane 图书馆，以查找比较机器人右半结肠切除术与传统腹腔镜右半结肠切除术的研究从数据库建立之日到 2022 年 8 月，右结肠癌的半结肠切除术。为了提取生存数据，使用 Kaplan-Meier 生存曲线的随机或固定效应模型计算具有 95% 置信区间 (CI) 的风险比 (HR)在纳入的研究中。所有计算和统计测试均使用 Review Manager 软件 5.4 版进行。本次荟萃分析共纳入了来自五项研究的 523 名患者（机器人右半结肠切除术，230 例；腹腔镜右半结肠切除术，293 例）。两组之间的患者特征没有显着差异。就病理特征而言，TNM 分期没有差异，并且在一项研究中，尽管机器人组收获了更多的淋巴结，但收获的淋巴结数量没有差异。汇总分析表明机器人和腹腔镜右半结肠切除术之间的无病生存率（HR 0.72，95% CI 0.46-1.13，p = 0.15）和总生存率（HR 0.73，95% CI 0.48-1.13，p = 0.16）没有显着差异右半结肠癌的机器人右半结肠切除术在长期肿瘤生存方面与传统腹腔镜右半结肠切除术相当。需要进行更多前瞻性、多中心、随机试验来确定机器人右半结肠切除术的肿瘤学安全性。© 2023。Springer Nature Switzerland AG。

The short-term outcomes of robotic right hemicolectomy for right colon cancer have been extensively studied in comparison to conventional laparoscopic right hemicolectomy. However, the long-term oncological outcomes of the two approaches have not been investigated, except in single-center retrospective studies. Therefore, this meta-analysis aimed to investigate the long-term oncological outcomes of robotic right hemicolectomy compared with those of laparoscopic right hemicolectomy for right colon cancer.We searched PubMed, EMBASE, and Cochrane Library for studies comparing robotic right hemicolectomy with conventional laparoscopic right hemicolectomy for right colon cancer from the date of database inception to August 2022. For survival data extraction, hazard ratios (HRs) with 95% confidence intervals (CI) were calculated using random- or fixed-effects models from the Kaplan-Meier survival curves in the included studies. All calculations and statistical tests were performed using Review Manager software, version 5.4.A total of 523 patients (robotic right hemicolectomy, 230; laparoscopic right hemicolectomy, 293) from five studies were included in this meta-analysis. There were no significant differences in patient characteristics between the two groups. In terms of pathological characteristics, TNM stage was not different and revealed no differences in the number of harvested lymph nodes even though a larger number of lymph nodes were harvested in the robotic group in one study. Pooled analyses demonstrated no significant difference in disease-free survival (HR 0.72, 95% CI 0.46-1.13, p = 0.15) and overall survival (HR 0.73, 95% CI 0.48-1.13, p = 0.16) between robotic and laparoscopic right hemicolectomy for right colon cancer.Robotic right hemicolectomy for right colon cancer is comparable with conventional laparoscopic right hemicolectomy in terms of long-term oncological survival. More prospective, multicenter, randomized trials are necessary to determine the oncologic safety of robotic right hemicolectomy.© 2023. Springer Nature Switzerland AG.