美国中央脑肿瘤登记处 (CBTRUS) 与疾病控制与预防中心和国家癌症研究所合作，是最大的基于人群的登记处，专门关注原发性脑肿瘤和其他中枢神经系统 (CNS) 肿瘤在美国 (US) 并代表整个美国人口。该报告包含有关原发性脑肿瘤的最新的基于人群的数据，并在完整性和准确性方面取代了所有以前的 CBTRUS 报告。所有比率均根据 2000 年美国标准人口进行年龄调整，并按每 100,000 人计算。所有恶性和非恶性脑部及其他 CNS 肿瘤的平均年龄调整发病率 (AAAIR) 为每 100,000 人 24.83 例（恶性 AAAIR=6.94，非恶性 AAAIR=17.88）。女性的总体比率高于男性（每 10 万人中 27.85 人对 21.62 人），非西班牙裔人的总体比率高于西班牙裔人（每 10 万人中 25.24 人对 22.61 人）。胶质瘤占所有肿瘤的26.3%。最常见的脑部和其他中枢神经系统恶性组织病理学是胶质母细胞瘤（占所有肿瘤的 14.2%，占所有恶性肿瘤的 50.9%），最常见的非恶性组织病理学是脑膜瘤（占所有肿瘤的 40.8%，占所有非恶性肿瘤的 56.2%）。 -恶性肿瘤）。胶质母细胞瘤在男性中更常见，脑膜瘤在女性中更常见。在儿童和青少年（0-19岁）中，所有原发性脑肿瘤和其他中枢神经系统肿瘤的发病率为每10万人中6.13例。 2016年至2020年间，有86,030人死于恶性脑肿瘤和其他中枢神经系统肿瘤。这意味着年平均死亡率为每10万人中4.42人，平均每年有17,206人死亡。恶性脑部和其他中枢神经系统肿瘤诊断后的五年相对生存率为 35.7%，非恶性脑部和其他中枢神经系统肿瘤的五年相对生存率为 91.8%。© 作者 2023。由牛津大学出版社代表神经肿瘤学会出版。版权所有。如需权限，请发送电子邮件至：journals.permissions@oup.com。

The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control and Prevention and the National Cancer Institute, is the largest population-based registry focused exclusively on primary brain and other central nervous system (CNS) tumors in the United States (US) and represents the entire US population. This report contains the most up-to-date population-based data on primary brain tumors available and supersedes all previous CBTRUS reports in terms of completeness and accuracy. All rates are age-adjusted using the 2000 US standard population and presented per 100,000 population. The average annual age-adjusted incidence rate (AAAIR) of all malignant and non-malignant brain and other CNS tumors was 24.83 per 100,000 population (malignant AAAIR=6.94 and non-malignant AAAIR=17.88). This overall rate was higher in females compared to males (27.85 versus 21.62 per 100,000) and non-Hispanic persons compared to Hispanic persons (25.24 versus 22.61 per 100,000). Gliomas accounted for 26.3% of all tumors. The most commonly occurring malignant brain and other CNS histopathology was glioblastoma (14.2% of all tumors and 50.9% of all malignant tumors), and the most common predominantly non-malignant histopathology was meningioma (40.8% of all tumors and 56.2% of all non-malignant tumors). Glioblastomas were more common in males, and meningiomas were more common in females. In children and adolescents (ages 0-19 years), the incidence rate of all primary brain and other CNS tumors was 6.13 per 100,000 population. There were 86,030 deaths attributed to malignant brain and other CNS tumors between 2016 and 2020. This represents an average annual mortality rate of 4.42 per 100,000 population and an average of 17,206 deaths per year. The five-year relative survival rate following diagnosis of a malignant brain and other CNS tumor was 35.7%, for a non-malignant brain and other CNS tumor the five-year relative survival rate was 91.8%.© The Author(s) 2023. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.