本研究的目的是确定罗马尼亚境内癌症热点分布的空间差异。此外，该研究旨在根据癌症类型跟踪癌症患病率和死亡率的普遍趋势。该研究涵盖 2008 年至 2017 年的时间范围，审查了所有 3,181 个领土行政单位。空间分布的分析依赖于两个关键参数。第一个参数“持续性”测量癌症患病率超过第 75 个百分位数阈值的持续时间。癌症患病率是指人群中在特定时间点被诊断患有癌症的总人数，包括新诊断病例（发生）和现有病例。第二个参数是持久性的时间连续性，计算癌症患病率持续超过第 75 个百分位数阈值的连续月份。值得注意的是，在低地地区，价值持续升高也很明显，与环境条件没有任何明显的直接联系。总之，这项工作通过帮助制定预防策略，同时促进对导致癌症的社会经济和环境因素的更深入理解，与区域卫生政策具有重大意义。© 2023 作者。 《GeoHealth》由 Wiley periodicals LLC 代表美国地球物理联盟出版。

The objective of this study was to identify spatial disparities in the distribution of cancer hotspots within Romania. Additionally, the research aimed to track prevailing trends in cancer prevalence and mortality according to a cancer type. The study covered the timeframe between 2008 and 2017, examining all 3,181 territorial administrative units. The analysis of spatial distribution relied on two key parameters. The first parameter, persistence, measured the duration for which cancer prevalence exceeded the 75th percentile threshold. Cancer prevalence refers to the total number of individuals in a population who have been diagnosed with cancer at a specific time point, including both newly diagnosed cases (occurrence) and existing cases. The second parameter, the time continuity of persistence, calculated the consecutive months during which cancer prevalence consistently surpassed the 75th percentile threshold. Notably, persistence of elevated values was also evident in lowland regions, devoid of any discernible direct connection to environmental conditions. In conclusion, this work bears substantial relevance to regional health policies, by aiding in the formulation of prevention strategies, while also fostering a deeper comprehension of the socioeconomic and environmental factors contributing to cancer.© 2023 The Authors. GeoHealth published by Wiley Periodicals LLC on behalf of American Geophysical Union.