最近的研究表明，滴虫病（人类最常见的非病毒性传播感染 (STI)）的病原体阴道毛滴虫可以在阴道内造成持续感染。阴道毛滴虫感染通常无症状，但可能产生不良后果，例如增加 HIV-1 感染和宫颈癌的风险。尽管如此，它仍然是一种未被充分研究的感染。持续性感染的潜在病原体是“假囊肿”，这是由多个实验室鉴定出的一种球形形式的阴道毛滴虫，并与相关物种（例如禽类寄生虫鸡毛滴虫和牛寄生虫胎儿毛滴虫）的持续存在有关。需要对假性囊肿和持续性阴道毛滴虫感染进行更多稳健且可重复的研究，这可能最终为如何更好地诊断和治疗滴虫病提供线索。版权所有 © 2023 Elsevier Ltd. 保留所有权利。

Recent studies have proposed that Trichomonas vaginalis, the causative agent of trichomoniasis [the most common nonviral sexually transmitted infection (STI) in humans] can establish persistent infections in the vagina. T. vaginalis infections are often asymptomatic but can have adverse consequences such as increased risk of HIV-1 infection and cervical cancer. Despite this, it remains an understudied infection. A potential agent of persistent infections is the 'pseudocyst', a spherical form of T. vaginalis identified by several laboratories and linked to persistence in related species such as the avian parasite Trichomonas gallinae and cattle parasite Tritrichomonas foetus. Additional robust and reproducible research on pseudocysts and persistent T. vaginalis infections is required, which may ultimately shed light on how to better diagnose and treat trichomoniasis.Copyright © 2023 Elsevier Ltd. All rights reserved.