尽管有有效的筛查策略以及预防性高危人乳头瘤病毒疫苗的开发和实施，宫颈癌仍然是一个重大的公共卫生负担。尽管这种疾病仍然存在于世界各地，包括工业化国家，但这种负担在没有充分发展的筛查和疫苗接种计划的资源贫乏国家最为明显。为此，世界卫生组织 (WHO) 积极关注消除宫颈癌，各国将在 2030 年之前实现客观指标。尽管需要增加疫苗接种和筛查才能实现彻底根除宫颈癌的目标正如世界卫生组织倡议所认识到的那样，治疗不仅需要在短期内继续有效，而且还需要改善结果。因此，正在评估改善主要治疗方案，包括对患有早期疾病的女性进行手术、对局部晚期宫颈癌患者进行放化疗修改，以及对复发或转移性表现的患者进行全身治疗。因此，我们强调了最近和持续关注的与改善宫颈癌结果相关的重要领域。版权所有 © 2023 美国妇产科学院。由 Wolters Kluwer Health, Inc. 出版。保留所有权利。

Despite effective screening strategies and the development and implementation of prophylactic high-risk human papillomavirus vaccination, cervical cancer remains a significant public health burden. This burden is most pronounced in under-resourced countries without fully developed screening and vaccination programs, although the disease remains present worldwide, including in industrialized countries. To that end, the World Health Organization (WHO) has an active focus on the elimination of cervical cancer, with objective metrics to be achieved by countries by the year 2030. Although increased vaccination and screening will be needed to approach potential eradication of cervical cancer, as recognized by the WHO initiative, treatment will need to continue to not only be effective in the near term, but to improve outcomes as well. Accordingly, assessments to improve primary treatment options, including surgery for women with early-stage disease, modification of chemoradiation for those with locally advanced cervical cancer, and systemic therapy for those with recurrent or metastatic presentations, are ongoing. Accordingly, we highlight important areas of both recent and ongoing focus as they relate to improving cervical cancer outcomes.Copyright © 2023 by the American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.