猫头鹰猴是新世界灵长类动物，属小型夜行性动物，最常用于疟疾的生物医学研究。心肌病和肾病是众所周知的常见疾病，导致其发病率和死亡率较高；对于影响胃肠道的病变知之甚少。对基林比较医学和研究中心 14 年期间（2008 年至 2022 年）的记录进行了查询，以确定直接导致 235 只提交尸检的成年猫头鹰猴死亡的自发性胃肠道疾病的实例。在 235 人中，10.6% (25/235) 患有胃肠道疾病，被列为导致发病和死亡的重要因素。诊断包括念珠菌病 (3/25)、胃胀 (4/25)、肠嵌顿和继发性缺血 (11/25)，其中包括肠套叠 (4/25)、肠系膜撕裂 (3/25)、绞窄性脂肪瘤 (2) /25）、肠扭转（1/25）和腹股沟疝（1/25）。影响空肠的肠腺癌 (4/25) 是最常见的肿瘤诊断。还诊断出口腔鳞状细胞癌（1/25）和肠淋巴瘤（2/25）。该报告提供了该物种中导致发病率和死亡率的自发病变的证据。

Owl monkeys are small nocturnal new world primates in the genus Aotus that are most used in biomedical research for malaria. Cardiomyopathy and nephropathy are well-described common diseases contributing to their morbidity and mortality; less is known about lesions affecting the gastrointestinal tract. Records from a 14-year period (2008-2022) at the Keeling Center for Comparative Medicine and Research were queried to identify instances of spontaneous gastrointestinal disease that directly contributed to the cause of death from the 235 adult owl monkeys submitted for necropsy. Of the 235, 10.6% (25/235) had gastrointestinal disease listed as a significant factor that contributed to morbidity and mortality. Diagnoses included candidiasis (3/25), gastric bloat (4/25), and intestinal incarceration and ischemia secondary (11/25), which included intussusception (4/25), mesenteric rent (3/25), strangulating lipoma (2/25), intestinal torsion (1/25), and an inguinal hernia (1/25). Intestinal adenocarcinomas affecting the jejunum (4/25) were the most common neoplasia diagnosis. Oral squamous cell carcinoma (1/25) and intestinal lymphoma (2/25) were also diagnosed. This report provides evidence of spontaneous lesions in the species that contribute to morbidity and mortality.