本系统综述旨在通过研究功能结果与舌切除范围之间的关系，深入了解口腔舌癌（OTC）中口腔舌的理想重建方法。在 Ovid MEDLINE、EMBASE 和 Web of Science 中进行了结构化检索。其中包括比较患者报告和皮瓣重建与非皮瓣重建之间口腔舌功能客观测量的研究。感兴趣的功能结果是言语产生、吞咽效率、舌头活动能力、整体生活质量和术后并发症。总共检索了九项研究并进行了严格评价。口腔舌切除 20% 或更少的患者通过非皮瓣重建具有较高的吞咽效率和言语清晰度，而舌缺损 40-50% 的患者自我报告或通过皮瓣修复表现出更好的吞咽功能。中间舌头缺陷（20-40% 舌头切除）的数据尚无定论，有几项研究报告了不同方法之间可比较的功能结果。需要进行一项纵向多机构前瞻性研究，严格控制舌切除范围和涉及的亚部位，以确定皮瓣重建在 OTC 中产生优异功能结果的舌切除百分比。版权所有 © 2023 Elsevier Ltd。保留所有权利。

This systematic review aims to provide insight into the ideal reconstructive approach of the oral tongue in oral tongue cancer (OTC) by investigating the relationship between functional outcomes and the extent of tongue resection. A structured search was performed in Ovid MEDLINE, EMBASE, and Web of Science. Studies comparing patient-reported and objective measurements of the oral tongue function between flap vs. non-flap reconstruction were included. Functional outcomes of interest were speech production, deglutition efficiency, tongue mobility, overall quality of life, and postoperative complications. A total of nine studies were retrieved and critically appraised. Patients with 20 % or less of oral tongue resected had superior swallowing efficiency and speech intelligibility with a non-flap reconstruction while patients with a tongue defect of 40-50 % self-reported or demonstrated better swallowing function with a flap repair. The data in intermediate tongue defects (20-40 % tongue resected) was inconclusive, with several studies reporting comparable functional outcomes between approaches. A longitudinal multi-institutional prospective study that rigidly controls the extent of tongue resected and subsites involved is needed to determine the percentage of tongue resected at which a flap reconstruction yields a superior functional result in OTC.Copyright © 2023 Elsevier Ltd. All rights reserved.