BCL6 微调长期肿瘤控制。
BCL6 fine-tunes long-term tumor control.
发表日期：2023 Oct 27
作者：
Shiki Takamura, Aneela Nomura, Masato Kubo
来源：
Science Immunology
摘要：
孙等人。提供了全面的证据，证明转录因子 BCL6 作为肿瘤中 CD8 祖细胞功能的看门人，并防止其过度终末分化，从而保留这种干细胞样群体以实现长期肿瘤控制。
Sun et al. provide comprehensive evidence that the transcription factor BCL6 functions as a gatekeeper for CD8+ progenitor cell function in tumors and prevents their excessive terminal differentiation, thereby preserving this stem-like population for long-term tumor control.