研究动态
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芬兰胃腺癌胃切除术后全国人群并发症发生率。

Population-based nationwide incidence of complications after gastrectomy for gastric adenocarcinoma in Finland.

发表日期:2023 Sep 05
作者: Emilia Putila, Olli Helminen, Mika Helmiö, Heikki Huhta, Aapo Jalkanen, Raija Kallio, Vesa Koivukangas, Arto Kokkola, Simo Laine, Elina Lietzen, Johanna Louhimo, Sanna Meriläinen, Vesa-Matti Pohjanen, Tuomo Rantanen, Ari Ristimäki, Jari V Räsänen, Juha Saarnio, Eero Sihvo, Vesa Toikkanen, Tuula Tyrväinen, Antti Valtola, Joonas H Kauppila
来源: BJS Open

摘要:

胃癌胃切除术后并发症的发生率尚不清楚。需要使用已建立的并发症分类进行更多基于人群的研究以进行国际比较。本研究的目的是评估胃癌胃切除术后术后并发症的人群发生率。这项基于芬兰国家食管胃癌队列的人群研究包括所有年龄至少 18 岁接受胃切除术的患者2005 年至 2016 年芬兰的腺癌。根据食管切除术并发症共识组的定义对术后 30 天和 90 天并发症的发生进行分级,并使用 Clavien-Dindo 量表评估并发症的严重程度。本研究共纳入 2196 名患者。术后 30 天内有 906 名患者(41.3%)出现术后并发症,术后 90 天内有 946 名患者(43.1%)出现术后并发症。 375 名(17.1%)患者出现 Clavien-Dindo III 级或以上并发症。食管切除术并发症共识组上层类别术后 90 天最常见的并发症是胃肠道并发症(n = 438;19.9%),包括吻合口瘘、感染性并发症(n = 377;17.2%)和肺部并发症(n = 335;17.2%)。 15.3%)并发症。术后 30 天内有 72 名患者(3.3%)发生术后死亡率,90 天内有 161 名患者(7.3%)发生术后死亡率。术后住院时间中位数为 9 天(四分位数间距 4-14)。术后并发症在所有类型的胃切除术中都很常见,大多数发生在术后前 30 天。这项研究向患者和护理人员告知胃切除术的预期结果。© 作者 2023。由牛津大学出版社代表 BJS Society Ltd 出版。
The incidence of postoperative complications after gastrectomy for gastric cancer is not well known. More population-based studies using established complication classifications are needed for international comparison. The aim of this study was to evaluate the population-based incidence of postoperative complications after gastrectomy for gastric cancer.This population-based study based on the Finnish National Esophago-Gastric Cancer Cohort included all patients at least 18 years of age undergoing gastrectomy for gastric adenocarcinoma in Finland during 2005-2016. The occurrence of complications 30 and 90 days after surgery was graded based on the Esophagectomy Complications Consensus Group definitions and the severity of complications was assessed using the Clavien-Dindo scale.This study included a total of 2196 patients. Postoperative complications occurred in 906 (41.3 per cent) of patients during 30 days after surgery and in 946 (43.1 per cent) during 90 days after surgery. Clavien-Dindo grade III or higher complications occurred in 375 (17.1 per cent) of patients. The most common complications 90 days after surgery by Esophagectomy Complications Consensus Group upper-level categories were gastrointestinal (n = 438; 19.9 per cent), including anastomotic leak, infectious (n = 377; 17.2 per cent) and pulmonary (n = 335; 15.3 per cent) complications. Postoperative mortality rate was occurred in 72 (3.3 per cent) patients within 30 days and in 161 (7.3 per cent) patients within 90 days after surgery. The median duration of postoperative hospital stay was 9 days (interquartile range 4-14).Postoperative complications are common across all types of gastrectomy and the majority occur during the first 30 postoperative days. This study informs the patients and caregivers of the expected outcomes of gastrectomy.© The Author(s) 2023. Published by Oxford University Press on behalf of BJS Society Ltd.