患者在住院期间死亡，报告病史中患有成血细胞增多症和梅毒。在对患者进行检查时，医生怀疑存在原发部位不明的恶性肿瘤，伴有多处转移性损伤，并伴有临床和实验室 TTP 体征（出血综合征、血小板减少症、囊性红细胞增多症和非免疫性溶血性贫血）。尽管进行治疗，一般患者的病情仍会随着多器官代偿失调体征的增加而逐渐恶化。在病程的最后阶段，在心脏骤停和出现临床死亡体征后，根据完整指导进行了CPR措施，但CRP没有积极作用。确认了生物性死亡。考虑到临床和实验室诊断标准（血小板减少症和微血管病性溶血性贫血）、病理检查数据（多发转移灶、炎症过程、肿瘤中毒、血栓形成）、慢性粒细胞白血病、前列腺癌的表现组合对于多发转移的癌症，三期梅毒是 TTP 启动的条件，这对于患者死亡的发展具有决定性的作用。

Patient, who died during the hospital stay, had hemoblastosis and syphilis in the reported medical history. While the patient was examined doctors suspected the presence of malignancy with unknown primary localization with multiple metastatic injuries with clinical and laboratory TTP signs (hemorrhagic syndrome, thrombocytopenia, shystocytosis, and non-immune hemolytic anemia). Despite treatment, the general patient's condition progressively worsens with increasing multiple organ decompensation signs. In the final stage of the disease course, after heart arrest and the appearance of clinical death signs CPR measures were performed according to complete guidance, but CRP had no positive effect. Biological death was constated. Considering the criteria of the diagnostic clinical and laboratory dyad (thrombocytopenia and microangiopathic hemolytic anemia), the data of the patholog¬ical examination (multiple metastatic lesions, inflammatory process, tumor intoxication, thrombosis), the combination of manifestations of chronic myeloid leukemia, prostate cancer with multiple metastases, tertiary syphilis served as a condition for the initiation of TTP, which was of decisive importance in the development of the patient's death.