癌症是一种神秘的疾病。除其他改变外，重要的是肿瘤细胞具有代谢改变。在癌细胞中常见的一种众所周知的代谢修饰被称为瓦尔堡效应。这种现象被定义为对葡萄糖摄取的高度偏好，并且即使在容易获得氧气的情况下，也会增加从葡萄糖中产生的乳酸。一些抗癌药物针对拟议的瓦尔堡效应，而一些饮食疗法也可以发挥类似的作用。然而，治疗特定癌症的最合适的饮食策略尚不清楚。本综述的目的是描述有关针对瓦尔堡效应的各种拟议饮食方案的影响的发现。有证据表明，将常规癌症疗法与基于饮食的策略相结合可能会改善癌症的治疗效果。然而，设计个体化疗法必须是我们的最终目标。© 作者 2023。由牛津大学出版社代表国际生命科学研究所出版。版权所有。如需权限，请发送电子邮件至：journals.permissions@oup.com。

Cancer is a mysterious disease. Among other alterations, tumor cells, importantly, have metabolic modifications. A well-known metabolic modification commonly observed in cancer cells has been termed the Warburg effect. This phenomenon is defined as a high preference for glucose uptake, and increased lactate production from that glucose, even when oxygen is readily available. Some anti-cancer drugs target the proposed Warburg effect, and some dietary regimens can function similarly. However, the most suitable dietary strategies for treating particular cancers are not yet well understood. The aim of this review was to describe findings regarding the impact of various proposed dietary regimens targeting the Warburg effect. The evidence suggests that combining routine cancer therapies with diet-based strategies may improve the outcome in treating cancer. However, designing individualized therapies must be our ultimate goal.© The Author(s) 2023. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.