荟萃分析的目的是评估和比较结直肠癌（CC）患者手术部位感染（SSI）的危险因素。分析了该荟萃分析的结果，并使用二分法或有争议的随机或固定效应模型计算了优势比 (OR) 和平均差 (MD) 与 95% 置信区间 (CI)。目前的荟萃分析纳入了 2001 年至 2023 年的 23 项检查，涵盖 89 859 例 CC。与 CC 患者受污染的手术部位伤口相比，清洁污染的手术部位伤口的感染率显着降低（OR，0.36；95% CI，0.20-0.64，p<0.001）。与女性 CC 患者相比，男性的 SSI 显着较高（OR，1.18；95% CI，1.12-1.24，p<0.001）。与 CC 患者评分 <3 相比，美国麻醉学会评分≥3 小时的 SSI 显着较高（OR，1.42；95% CI，1.18-1.71，p<0.001）。与体重指数 <25 的 CC 患者相比，体重指数≥25 的 SSI 显着更高（OR，1.54；95% CI，1.11-2.14，p = 0.01）。与不存在造口的 CC 患者相比，存在造口的 SSI 率显着较高（OR，2.28；95% CI，1.37-3.79，p = 0.001）。与开腹手术相比，CC 患者腹腔镜手术的 SSI 显着降低（OR，0.68；95% CI，0.59-0.78，p<0.001）。与不存在糖尿病的 CC 患者相比，存在糖尿病的 SSI 率显着较高（OR，1.24；95% CI，1.15-1.33，p<0.001）。在手术时间<3小时和≥3小时之间的CC患者中，有无输血（OR，1.07；95% CI，0.75-1.51，p=≥0.72）时，SSI率没有显着差异（OR，1.07；95% CI，0.75-1.51，p = 0.72） , 1.60; 95% CI, 0.69-3.66, p = 0.27) 以及是否存在既往剖腹手术 (OR, 1.47; 95% CI, 0.93-2.32, p = 0.10)。检查数据显示，伤口污染、男性、美国麻醉学会评分≥3小时、体重指数≥25、造口、开放手术和糖尿病都是CC患者发生SSI的危险因素。然而，手术时间、输血和既往剖腹手术未发现是 CC 患者发生 SSI 的危险因素。然而，鉴于几项比较的选定研究数量较少，应考虑其价值。© 2023 作者。 《国际伤口杂志》由 Medicalhelplines.com Inc 和 John Wiley 出版

The purpose of the meta-analysis was to evaluate and compare the surgical site infection (SSI) risk factors in patients with colorectal cancer (CC). The results of this meta-analysis were analysed, and the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) were calculated using dichotomous or contentious random or fixed-effect models. For the current meta-analysis, 23 examinations spanning from 2001 to 2023 were included, encompassing 89 859 cases of CC. Clean-contaminated surgical site wounds had significantly lower infections (OR, 0.36; 95% CI, 0.20-0.64, p < 0.001) compared to contaminated surgical site wounds in patients with CCs. Males had significantly higher SSIs (OR, 1.18; 95% CI, 1.12-1.24, p < 0.001) compared to females in patients with CC. American Society of Anesthesiology score ≥3 h had a significantly higher SSI (OR, 1.42; 95% CI, 1.18-1.71, p < 0.001) compared to <3 score in patients with CCs. Body mass index ≥25 had significantly higher SSIs (OR, 1.54; 95% CI, 1.11-2.14, p = 0.01) compared to <25 in patients with CCs. The presence of stoma creation had a significantly higher SSI rate (OR, 2.28; 95% CI, 1.37-3.79, p = 0.001) compared to its absence in patients with CC. Laparoscopic surgery had significantly lower SSIs (OR, 0.68; 95% CI, 0.59-0.78, p < 0.001) compared to open surgery in patients with CC. The presence of diabetes mellitus had a significantly higher SSI rate (OR, 1.24; 95% CI, 1.15-1.33, p < 0.001) compared to its absence in patients with CCs. No significant difference was found in SSI rate in patients with CCs between <3 and ≥3 h of operative time (OR, 1.07; 95% CI, 0.75-1.51, p = 0.72), between the presence and absence of blood transfusion (OR, 1.60; 95% CI, 0.69-3.66, p = 0.27) and between the presence and absence of previous laparotomies (OR, 1.47; 95% CI, 0.93-2.32, p = 0.10). The examined data revealed that contaminated wounds, male sex, an American Society of Anesthesiology score ≥3 h, a body mass index ≥25, stoma creation, open surgery and diabetes mellitus are all risk factors for SSIs in patients with CC. However, operative time, blood transfusion and previous laparotomies were not found to be risk factors for SSIs in patients with CC. However, given that several comparisons had a small number of chosen research, consideration should be given to their values.© 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.