单克隆抗体 (mAb) 的发展也使研究人员能够更好地了解疾病的复杂性，并为疑难病症找到新的治疗方法。使用单克隆抗体，研究人员可以识别并靶向体内参与疾病过程的特定分子。这使得更有针对性的治疗方法成为可能，从而改善了许多患者的治疗结果。这一假设是开发可治疗多种疾病的单克隆抗体的基础。在过去的二十年里，治疗性单克隆抗体已被开发用于治疗癌症、自身免疫性疾病、心血管疾病和代谢疾病。例如，使用单克隆抗体可以改善类风湿性关节炎、多发性硬化症和克罗恩病的治疗效果。然而，在生物系统中递送单克隆抗体仍然是药物递送的重大挑战。这是由于它们体积大、循环稳定性低以及难以在靶细胞中实现所需的作用。单克隆抗体 (mAb) 是生物系统中的重要工具，因为它们可用于将药物递送至特定细胞类型或组织。已经开发出单克隆抗体生产的克隆方法来生产具有治疗潜力的单克隆抗体。因此，本综述重点关注单克隆抗体（mAb）在生物系统中的开发和药物递送，包括克隆方法、各种药物递送技术、制剂生产技术及其在多种疾病中的应用。版权所有©边沁科学出版社；如有任何疑问，请发送电子邮件至 epub@benthamscience.net。

The development of Monoclonal antibodies (mAbs) has also allowed researchers to understand the complexity of diseases better and find new treatments for difficult-to-treat conditions. Using mAbs, researchers can identify and target specific molecules in the body involved in the disease process. This has allowed for a more targeted treatment approach, which has resulted in improved outcomes for many patients. This hypothesis has been the basis for the development of mAbs that can target an array of illnesses. In the past two decades, therapeutic mAbs have been developed to treat cancer, autoimmune diseases, cardiovascular diseases, and metabolic diseases. For instance, using mAbs has improved outcomes in treating rheumatoid arthritis, multiple sclerosis, and Crohn's disease. However, delivering mAbs in biological systems remains a significant challenge in drug delivery. This is due to their large size, low stability in circulation, and difficulties in achieving their desired action in the target cells. Monoclonal antibodies (mAbs) are an essential tool in biological systems, as they can be used to deliver drugs to specific cell types or tissues. Cloning methods of monoclonal antibody production have been developed to produce mAbs with therapeutic potential. Hence, the present review focused on the development and drug delivery of Monoclonal antibodies (mAbs) in biological systems, which includes cloning methods, various drug delivery technologies, formulation production technology, and its applications in multiple diseases were focused for this review.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.