坏死性胃炎是一种罕见疾病，患病率未知，诊断通常是在急腹症患者剖腹探查或尸检过程中偶然发现的。呈现坏死性胃炎的临床病例，这是一种罕见疾病，在免疫功能低下的患者中应予以考虑具有相关危险因素。7岁男学生被诊断患有T前体急性淋巴细胞白血病，按照PETHEMA 2013方案完成诱导化疗周期。他出现了 12 天的症状，其特征是上腹疼痛和呕吐，最初怀疑是急性胰腺炎，但通过正常胰酶和腹部计算机断层扫描排除了这一可能性。由于怀疑与类固醇相关的酸性消化病，开始使用质子泵抑制剂和促动力剂治疗。考虑到消化不良伴有警报信号，例如中性粒细胞减少症进展、C反应蛋白增加和临床恶化，进行了食管胃十二指肠镜检查（EGD），经组织病理学证实符合坏死性胃炎。他接受了药物管理、零方案和肠外支持，影像学控制显示病情逐渐改善。禁食 30 天后，开始肠内营养，耐受性良好，并进行门诊随访。改善后，化疗计划完成，2年后完全缓解，无并发症。坏死性胃炎是一种罕见的疾病，在该病例中描述的危险因素是免疫功能低下、既往接受过皮质类固醇和细胞毒治疗，以及可能暴露于压力环境中住院期间。早期诊断和治疗决定了良好的预后。

Necrotizing gastritis is an infrequent entity with unknown prevalence, the diagnosis is often incidental during exploratory laparotomy or autopsies of patients with acute abdomen.To present a clinical case of necrotizing gastritis, a rare entity that should be taken into account in the context of immunocompromised patients with associated risk factors.7-year-old male schoolboy diagnosed with T-precursor acute lymphoid leukemia, finishing induction chemotherapy cycle with PETHEMA 2013 protocol. He presented 12 days of symptoms characterized by epigastric abdominal pain and vomiting, initially acute pancreatitis was suspected, ruled out by normal pancreatic enzymes and abdominal computed tomography. Due to suspicion of acid peptic disease associated with steroids, treatment with proton pump inhibitors and prokinetics was started. Considering dyspepsia with alarm signs, such as progression of neutropenia, increased C-reactive protein and clinical deterioration, esophagogastroduodenoscopy (EGD) was performed, compatible with necrotizing gastritis, confirmed by histopathology. He received pharmacological management, zero regimen and parenteral support, and progressive improvement was evidenced in imaging controls. After fasting for 30 days, enteral nutrition was started, well tolerated, with ambulatory follow-up. After improvement, chemotherapy plan was completed, highlighting complete remission, without complications after 2 years.Necrotizing gastritis is a rare entity, in the case described the risk factors were immunocompromise, previous management with corticosteroids and cytotoxic therapy, and possibly, exposure to stressful situations during hospitalization. Early diagnosis and treatment determined a favourable prognosis.