研究动态
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表现为粟粒性面部丘疹的原位滤泡 B 细胞肿瘤:独特的临床表现和自发消退。

In Situ Follicular B-Cell Neoplasm Presenting as Miliary Facial Papules: A Unique Clinical Presentation and Spontaneous Regression.

发表日期:2023 Oct 26
作者: Prashant Bavi, Adnan Mansoor, Iwona Auer, Jori Hardin
来源: MEDICINE & SCIENCE IN SPORTS & EXERCISE

摘要:

原位滤泡性 B 细胞肿瘤 (ISFN) 是滤泡性淋巴瘤的一种变体,表现为淋巴结活检或切除标本中的偶然组织学发现。 ISFN 呈现出在淋巴结或结外部位的生发中心内强烈表达 BCL2 和 CD10 的 B 细胞群。遗传分析显示 t(14;18) 易位。在此,我们报道了一名年轻女性的 ISFN 病例,其表现为军事性和粘连性面部丘疹,在产后自然消退。据我们所知,这是该罕见实体参与皮肤部位的唯一报告。版权所有 © 2023 Wolters Kluwer Health, Inc. 保留所有权利。
In situ follicular B-cell neoplasm (ISFN) is a variant of follicular lymphoma, presenting as an incidental histologic finding in lymph node biopsy or excisional specimens. ISFN presents with a B-cell population that strongly expresses BCL2 and CD10 within the germinal centers of a lymph node or extranodal site. Genetic analysis shows t(14;18) translocation. Herein, we report a case of ISFN presenting as military and agminated facial papules in a young woman, which resolved spontaneously in the postpartum period. To our knowledge, this is the only report of a cutaneous site of involvement of this rare entity.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.