口腔癌患者的牙科康复对于良好的口腔健康相关生活质量 (OHRQoL) 至关重要。患者特异性牙种植体适合治疗肿瘤相关的骨缺损，从而获得令人满意的 OHRQoL。然而，关于肿瘤照射后的临床结果和 OHRQoL 的知识尚缺乏。我们进行了一项回顾性分析，以评估 8 名患者的临床结果和 OHRQoL，这些患者在口腔癌手术治疗后接受患者特异性牙种植体和种植体支持的假牙，并附加额外的治疗。辐照。 OHRQoL 评估采用德国长版口腔健康影响概况 (OHIP) 问卷 (OHIP-G53) 进行。临床检查显示，所有患者的牙齿康复均成功，仅有轻微损伤。没有观察到植入物的稳定性和功能受到限制。所有患者的 OHIP 总分均显示可接受的 OHRQoL，但这在上颌或下颌治疗的患者之间有所不同。关于不良事件“咀嚼困难”、“抓食物”、“下巴酸痛”、“斑点酸痛”和“言语不清”的单项总分被检测为最差，并且与疼痛相关的 OHIP 维度被证明下颌治疗后 OHRQoL 较差，得分最高（其次是功能限制、身体残疾和社会心理影响）。其他维度总分总体较低，并且在患者中分布几乎相等。使用患者特异性牙种植体对受辐射的口腔癌患者进行牙科康复可能是合适的，从而获得可接受的 OHRQoL。然而，将种植体植入上颌似乎更有利。有必要对患者特异性牙种植体进行进一步研究以验证当前结果。版权所有 © 2023。由 Elsevier Masson SAS 出版。

Dental rehabilitation in oral cancer patients is essential for good oral health-related quality of life (OHRQoL). Patient-specific dental implants are suitable for treating tumor-related bony defects, resulting in satisfactory OHRQoL. However, knowledge concerning the clinical outcome and OHRQoL following tumor irradiation is lacking.A retrospective analysis was carried out to evaluate clinical outcomes and OHRQoL in eight patients who received patient-specific dental implants and implant-supported dentures after surgical treatment for oral cancer with additional irradiation. OHRQoL assessment was performed using the German long version of the oral health impact profile (OHIP) questionnaire (OHIP-G53).Clinical examination revealed successful dental rehabilitation in all the patients with only minor impairments. Restricted stability and function of implants were not observed. OHIP sum-scores of all the patients indicated acceptable OHRQoL, but this varied between patients treated in the upper or lower jaw. Single-item sum-scores concerning the adverse events "difficulty in chewing," "food catching," "sore jaw," "sore spots," and "unclear speech" were detected to be the worst, and pain-related OHIP dimensions demonstrated the highest scores (followed by functional limitation, physical disability, and psychosocial impact) with a worse OHRQoL following lower jaw treatment. Other dimension sum-scores were overall lower and nearly equally distributed in patients.Dental rehabilitation of irradiated oral cancer patients using patient-specific dental implants may be suitable, leading to acceptable OHRQoL. However, implant insertion in the upper jaw seems to be more favorable. Further studies on patient-specific dental implants are warranted to validate the current results.Copyright © 2023. Published by Elsevier Masson SAS.