蛋白 C 缺乏是一种罕见的血液疾病，会增加血栓栓塞的风险，导致深静脉血栓、肺栓塞和中风。节段性睾丸梗死也是一种罕见疾病，病因尚不清楚。该病例是一名 50 多岁的男性，患有蛋白质 C 缺乏症，并患上节段性睾丸梗塞。该患者接受保守治疗，未进行手术干预。他接受了连续超声监测，结果显示睾丸从正常进展到节段性梗塞并最终消退。该病例强调，蛋白 C 缺乏会导致睾丸梗塞，而多学科方法可以帮助避免不必要的手术，并获得良好的结果。对于已有血栓形成倾向的患者，在排除恶性肿瘤和感染后，应考虑节段性梗死。在这种情况下，通过重复超声检查和随访进行保守治疗可能是适当的。© BMJ Publishing Group Limited 2023。不得商业重复使用。请参阅权利和权限。由英国医学杂志出版。

Protein C deficiency is a rare blood disorder that increases the risk of thromboembolism, resulting in deep vein thrombosis, pulmonary embolisms and strokes. Segmental testicular infarction is also a rare condition with unclear aetiology. This case presents a man in his 50s with protein C deficiency who developed a segmental testicular infarction. The patient was managed conservatively, without surgical intervention. He was monitored with serial ultrasound, which demonstrated progression from normal testis to segmental infarction and eventually resolution. The case highlights that protein C deficiency can cause testicular infarction, and a multidisciplinary approach can help avoid unnecessary surgery with excellent outcomes. Segmental infarction should be considered in patients with pre-existing thrombophilias after excluding malignancy and infection. Conservative management with repeat ultrasonography and follow-up can be appropriate in such cases.© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.