原发性纵隔大B细胞淋巴瘤并发强直性肌营养不良[J].
[Primary mediastinal large B-cell lymphoma complicated with myotonic dystrophy].
发表日期：2023
作者：
Kodai Hasegawa, Ayako Matsumura, Kengo Katsuki, Masahiro Akimoto, Takayuki Sakuma, Yuki Nakajima, Takuya Miyazaki, Shin Fujisawa, Hideaki Nakajima
来源：
Immunity & Ageing
摘要：
一名患有强直性肌营养不良 (DM) 的 39 岁女性出现晕厥，被诊断为原发性纵隔大 B 细胞淋巴瘤，临床 IA 期。 PET-CT 显示上纵隔肿块，FDG 摄取量高（SUVmax，14.8）。她患有与糖尿病相关的肌肉无力，但她的表现状态得以保留。她接受了 6 个周期的剂量调整 EPOCH-R 治疗和针对残余肿块的局部照射，没有发生严重不良事件或晕厥复发。糖尿病患者在接受淋巴瘤治疗时应监测心脏事件和肌肉无力。
A 39-year-old woman with myotonic dystrophy (DM) presented with syncope and was diagnosed with primary mediastinal large B-cell lymphoma, clinical stage IA. PET-CT revealed an upper mediastinal mass with high FDG uptake (SUVmax, 14.8). She had muscle weakness associated with DM, but her performance status was preserved. She was treated with 6 cycles of dose-adjusted EPOCH-R therapy and localized irradiation for the residual mass, without severe adverse events or recurrence of syncope. Patients with DM should be monitored for cardiac events and muscle weakness when undergoing lymphoma treatment.