我们报告了一名患者出现与 HIV 感染相关的多种泌尿科合并症的病例。一名53岁男性被诊断患有艾滋病毒感染和艾滋病。 13 年后，发现微量血尿，计算机断层扫描 (CT) 显示尿石症和左肾肿瘤，疑似肾细胞癌。最初，他接受了经尿道碎石术。石头分析表明，这块石头是由阿扎那韦制成的。随后他接受了腹腔镜左肾部分切除术。病理诊断为乳头状2型肾细胞癌。三年后，随访 CT 显示右肾盂肿瘤。由于右侧输尿管镜检查显示肿瘤为乳头状，我们诊断为肾盂癌，并决定进行腹腔镜右侧肾输尿管根治性切除术。经病理诊断，其肾盂肿瘤为尿路上皮癌。肾输尿管切除术后膀胱内复发两次。随访期间，他的肾功能逐渐恶化，我们怀疑HIV肾病是恶化的原因之一。 71岁时开始进行血液透析。

We report a case of a patient who developed several urological comorbidities associated with HIV infection. A 53-year-old male was diagnosed with HIV infection and AIDS. After 13 years, microhematuria was found and computed tomography (CT) revealed urolithiasis and a left renal tumor suspected of being renal cell carcinoma. Initially, he underwent transurethral lithotripsy. Stone analysis indicated that the stone was made of atazanavir. Then he received laparoscopic left partial nephrectomy. The pathological diagnosis was papillary type 2 renal cell carcinoma. Three years later, follow-up CT revealed a right renal pelvic tumor. Since right ureteroscopy showed that the tumor was papillary we diagnosed it as renal pelvic cancer and decided to perform laparoscopic right radical nephroureterectomy. His renal pelvic tumor was determined to be urothelial carcinoma by the pathological diagnosis. Intravesical recurrence occurred twice after the nephroureterectomy. His renal function gradually deteriorated during follow-up and we suspected that HIV nephrosis was one of the reasons for the deterioration. Hemodialysis was initiated at the age of 71.