宫颈癌是全球第四大常见女性恶性肿瘤，也是一种复杂的疾病，通常始于 HPV 感染。其发展涉及各种遗传和表观遗传改变。目前的宫颈癌治疗由于其严重的副作用而效果并不令人满意，因此需要安全、有效的预防和治疗方式。植物化学物质已在宫颈癌的预防和治疗中得到解决，进一步了解宫颈癌发病机制的表观遗传学对于研究新的预防和治疗方式至关重要。解决潜在植物化学物质的表观遗传机制将提供它们单独或组合使用的概述。本综述的主要目的是强调植物化学物质在宫颈癌治疗中的表观遗传效应。

Cervical cancer is the fourth most common female malignancy worldwide and a complex disease that typically starts with HPV infection. Various genetic and epigenetic alterations are implicated in its development. The current cervical cancer therapies have unsatisfactory outcomes due to their serious adverse effects, necessitating the need for safe, effective preventive and therapeutic modalities. Phytochemicals have been addressed in cervical cancer prevention and treatment, and further understanding the epigenetics of cervical cancer pathogenesis is critical to investigate new preventive and therapeutic modalities. Addressing the epigenetic mechanisms of potential phytochemicals will provide an overview of their use individually or in combination. The primary aim of this review is to highlight the epigenetic effects of the phytochemicals addressed in cervical cancer therapy.