中药Aralia elata (Miq.) Seem.，又名东北楤木，具有“益气安神、固精补肾、祛风活血”的功效。用于治疗神经衰弱、阳虚气虚、肾气虚、脾阳虚、水湿郁滞、口渴、跌打损伤等。龙牙皂甙是发挥药理作用的主要成分。从现代药理科学的角度来看，龙牙楤木具有广泛的功效，包括通过调节离子稳态来抗心肌缺血和减轻继发性心肌缺血再灌注损伤，通过抑制增殖、促进细胞凋亡和增强免疫力来抗肿瘤活性，降血糖等。通过调节糖脂代谢发挥降脂作用，以及保肝、神经保护、抗炎/镇痛作用。对龙牙楤木药理机制的研究将有利于其今后的开发和应用。本文综述了近二十年来国内外龙牙楤木的研究进展，并提出了进一步研究的新方向。

The traditional Chinese medicine Aralia elata (Miq.) Seem., also known as Aralia mandshurica, has the effect of "tonifying Qi and calming the mind, strengthening the essence and tonifying the kidneys, and dispelling wind and invigorating blood circulation". It is used in the treatment of neurasthenia, Yang deficiency and Qi deficiency, kidney Qi deficiency, spleen Yang deficiency, water-dampness stagnation, thirst, and bruises. Aralia elata saponins are the main components for the pharmacological effects. From the perspective of modern pharmacological science, Aralia elata has a wide range of effects, including anti-myocardial ischaemia and alleviation of secondary myocardium ischemic reperfusion injury by regulating ionic homeostasis, anti-tumor activity by inhibiting proliferation, promoting apoptosis and enhancing immunity, hypoglycemia and lipid lowering effects by regulating glucose and lipid metabolism, and hepato-protective, neuroprotective, anti-inflammatory/analgesic effects. The studies on pharmacological mechanisms of Aralia elata will be conducive to its development and application in the future. This article reviews the research progress of Aralia elata domestically and internationally in the last two decades and proposes new directions for further research.