研究动态
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对癌症患者常见的患者报告的身体功能结果测量的分数进行等百分位等同。

Equipercentile equating of scores from common patient-reported outcome measures of physical function in patients with cancer.

发表日期:2023 Oct 31
作者: Maria Rothmund, Micha J Pilz, Lisa Schlosser, Juan I Arraras, Mogens Groenvold, Bernhard Holzner, Marieke van Leeuwen, Morten Aa Petersen, Heike Schmidt, Teresa Young, Matthias Rose, David Cella, Johannes M Giesinger,
来源: JOURNAL OF CLINICAL EPIDEMIOLOGY

摘要:

提供癌症患者常用 PROM 的身体功能 (PF) 评分的等百分位数,以促进数据汇集和比较。来自五个欧洲国家的成年癌症患者完成了 EORTC CAT Core、EORTC QLQ-C30、FACT-G、SF-36 ,以及 PROMIS 物理功能 20a 简写形式。 R 包“equate”用于建立双变量等级相关性至少为 0.75 的 PF 评分转换表。总共有 953 名癌症患者(平均年龄 58.9 岁,54.7% 男性)参与。 EORTC CAT Core、EORTC QLQ-C30、SF-36 和 PROMIS 的 PF 分数之间的双变量等级相关性均高于 0.85,但 FACT-G 低于 0.69。除 FACT-G 之外的所有衡量标准均建立了换算表。这些表格表明一个 PROM 中的哪个分数与另一个 PROM 中的分数最匹配,并提供转换分数的标准误差。我们的分析表明,可以将来自 EORTC 测量(CAT 和 QLQ-C30)的 PF 分数与 PROMIS 和 SF-36 联系起来而 FACT-G 的物理域似乎有所不同。建立的转换表可用于比较使用不同 PROM 的临床研究的结果或汇总数据。版权所有 © 2023 作者。由爱思唯尔公司出版。保留所有权利。
To provide equipercentile equating of physical function (PF) scores from frequently used PROMs in cancer patients to facilitate data pooling and comparisons.Adult cancer patients from five European countries completed the EORTC CAT Core, EORTC QLQ-C30, FACT-G, SF-36, and the PROMIS Physical Function 20a short form. The R package "equate" was used to establish conversion tables of PF scores on those measures with a bivariate rank correlation of at least 0.75.In total, 953 patients with cancer (mean age 58.9 years, 54.7% men) participated. Bivariate rank correlations between PF scores from the EORTC CAT Core, EORTC QLQ-C30, SF-36, and PROMIS were all above 0.85, but below 0.69 for the FACT-G. Conversion tables were established for all measures but the FACT-G. These tables indicate which score from one PROM best matches the score from another PROM and provide standard errors of converted scores.Our analysis indicates that linking of PF scores from both EORTC measures (CAT and QLQ-C30) with PROMIS and SF-36 is possible whereas the physical domain of the FACT-G seems to be different. The established conversion tables may be used for comparing results or pooling data from clinical studies using different PROMs.Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.