接受机械血栓切除术 (MT) 治疗的患者缺乏磁敏感血管征 (SVS) 与 3 个月后不良的放射学和临床结果相关。癌症等潜在疾病被认为会影响 SVS 状态，并可能影响长期结果。我们的目的是评估 SVS 状态作为 MT 治疗患者长期结局的独立预测因子。SVS 状态是在 2010 年至 2018 年间在综合性卒中中心连续接受 MT 治疗的患者中回顾性确定的。长期死亡率和不良预后的预测因子分别使用多变量 Cox 和逻辑回归确定长达 8 年的功能结果（改良 Rankin 量表 (mRS) ≥3）。在纳入的 558 名患者中，13% (n=71) 不存在 SVS，87% (n=71) 存在 SVS。 n=487) 的基线成像。没有 SVS 的患者在中风时更有可能患有活动性癌症 (P=0.003) 和糖尿病 (P<0.001)。中位长期随访时间为 1058 天（IQR 533-1671 天）。在对活动性癌症和糖尿病等进行调整后，缺乏 SVS 与长期死亡率（调整后 HR (aHR) 2.11，95%CI 1.35 至 3.29）和长期功能结果不佳（调整后 OR（ aOR) 2.90, 95%CI 1.29 至 6.55)。未接受 SVS 的 MT 治疗患者的长期死亡率较高，长期功能结果较差。看来这种关联不能仅用合并症来解释，需要进一步研究。© 作者（或其雇主）2023。禁止商业重复使用。请参阅权利和权限。英国医学杂志出版。

The absence of the susceptibility vessel sign (SVS) in patients treated with mechanical thrombectomy (MT) is associated with poor radiological and clinical outcomes after 3 months. Underlying conditions, such as cancer, are assumed to influence SVS status and could potentially impact the long-term outcome. We aimed to assess SVS status as an independent predictor of long-term outcomes in MT-treated patients.SVS status was retrospectively determined in consecutive MT-treated patients at a comprehensive stroke center between 2010 and 2018. Predictors of long-term mortality and poor functional outcome (modified Rankin Scale (mRS) ≥3) up to 8 years were identified using multivariable Cox and logistic regression, respectively.Of the 558 patients included, SVS was absent in 13% (n=71) and present in 87% (n=487) on baseline imaging. Patients without SVS were more likely to have active cancer (P=0.003) and diabetes mellitus (P<0.001) at the time of stroke. The median long-term follow-up time was 1058 days (IQR 533-1671 days). After adjustment for active cancer and diabetes mellitus, among others, the absence of SVS was associated with long-term mortality (adjusted HR (aHR) 2.11, 95% CI 1.35 to 3.29) and poor functional outcome in the long term (adjusted OR (aOR) 2.90, 95% CI 1.29 to 6.55).MT-treated patients without SVS have higher long-term mortality rates and poorer long-term functional outcome. It appears that this association cannot be explained by comorbidities alone, and further studies are warranted.© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.