天然存在的类黄酮长期以来一直被用作开发新药的基本模板和功能性食品的关键成分。黄芪甲苷 (AG) 是一种天然黄酮类化合物，可以从多种常见的食用植物中分离出来，例如绿茶、桑树和菟丝子的种子。值得注意的是，AG具有广泛的药理活性，对多种疾病具有治疗作用，涵盖癌症、骨关节炎、骨质疏松、溃疡性结肠炎、乳腺炎、肥胖、糖尿病、糖尿病并发症、缺血/再灌注损伤、神经病变、呼吸系统疾病等。疾病、生殖系统疾病。本文综述了AG的天然来源和药代动力学，系统总结了AG治疗多种疾病的药理活性和潜在机制，以期推动AG作为功能食品的发展，为其在疾病治疗中的临床应用提供参考。 .版权所有 © 2023 陈、钟、秦、静、刘、李和彭。

Naturally occurring flavonoids have long been utilized as essential templates for the development of novel drugs and as critical ingredients for functional foods. Astragalin (AG) is a natural flavonoid that can be isolated from a variety of familiar edible plants, such as the seeds of green tea, Morus alba L., and Cuscuta chinensis. It is noteworthy that AG has a wide range of pharmacological activities and possesses therapeutic effects against a variety of diseases, covering cancers, osteoarthritis, osteoporosis, ulcerative colitis, mastitis, obesity, diabetes mellitus, diabetic complications, ischemia/reperfusion injury, neuropathy, respiratory diseases, and reproductive system diseases. This article reviewed the natural source and pharmacokinetics of AG and systematically summarized the pharmacological activities and potential mechanisms of AG in treating diverse diseases in order to promote the development of AG as a functional food, in doing so providing references for its clinical application in disease therapy.Copyright © 2023 Chen, Zhong, Qin, Jing, Liu, Li and Peng.