在美国 (US) 的一大群患有淋巴瘤的青少年和年轻人 (AYA) 中，研究了非生物因素 (NBF) 对生存的影响。我们发现，即使在调整了影响生存的其他因素后，与有保险的受益人相比，患有经典霍奇金淋巴瘤 (cHL) 和非霍奇金淋巴瘤 (NHL) 的未参保和医疗补助 AYA 受益人的死亡风险显着增加。与非西班牙裔白人 (NHW) 患者相比，患有 cHL 和 NHL 的非西班牙裔黑人 (NHB) 患者的死亡风险也有所增加，但是，只有患有 NHL 的西班牙裔患者的死亡风险显着增加，而那些cHL 则不然。居住在低收入县的 NHL AYA 患者死亡风险增加。 NBF 与生存率的密切相关性表明有机会通过改善美国的护理机会/质量来提高 AYA 淋巴瘤患者的生存率。版权所有 © 2023 Dhir、Epperla、Costa 和 Xavier。

The impact of nonbiological factors (NBF) on survival was investigated in a large cohort of adolescents and young adults (AYA) with lymphoma in the United States (US). We found that uninsured and Medicaid AYA beneficiaries with classical Hodgkin lymphoma (cHL) and non-Hodgkin lymphoma (NHL) are at significantly increased risk of death when compared with their insured counterpart even after adjustment for other factors affecting survival. Increased risk of death was also noted for Non-Hispanic Black (NHB) patients with cHL and NHL when compared to Non-Hispanic White (NHW) patients, however, only Hispanic patients with NHL were found to have a significantly increased mortality risk while those with cHL were not. NHL AYA patients residing in lower-income counties are at increased risk of death. The strong association of NBF with survival indicates opportunities to improve the survival of AYA lymphoma patients by improving access/quality of care in the US.Copyright © 2023 Dhir, Epperla, Costa and Xavier.