研究动态
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番石榴植物中存在的植物化学物质及其药用活性机制的综述。

Review of Phytochemicals Present in Psidium guajava Plant and Its Mechanism of Action on Medicinal Activities.

发表日期:2023 Oct
作者: Dhanshree M Joshi, Swanand S Pathak, Shraddha Banmare, Sweza S Bhaisare
来源: CLINICAL PHARMACOLOGY & THERAPEUTICS

摘要:

几个世纪以来,草药一直被用来治疗各种人类疾病,而番石榴(桃金娘科),俗称番石榴,是一种值得注意的药用植物,具有显着的药理潜力。在印度,特别是在传统药物获取有限的农村地区,番石榴植物的各个部分,包括其叶子、树皮、根和果实,已被利用其治疗特性来解决各种健康问题。 Psidium guajava Linn 被证明是重要营养素以及生物活性化合物的宝贵储存库,例如 α-萜品醇、β-石竹烯(反式石竹烯)、芦丁、α-葎草烯、齐墩果酸、类黄酮和槲皮素。这些成分表现出多种药用活性,包括抗炎、抗癌、抗支气管炎、抗增殖、抗肿瘤、抗菌和抗糖尿病作用。番石榴植物的各个方面都具有经济意义,并且被大规模种植。在分类学上,番石榴可分为植物界、木兰植物门、木兰纲、蔷薇亚纲、桃金娘目、桃金娘科、桃金娘亚科、桃金娘族、桃金娘属、番石榴种。番石榴对各种土壤和环境条件的适应性使得种植相对容易,从而可以快速生产果实。它在印度的广泛种植归因于其多种商业用途。为了全面了解这种植物如何有效解决印度民众遇到的一系列健康挑战,本综述深入研究了其多方面的治疗特性,强调了其在医疗保健实践中的重要性。研究人员正在进行的研究工作不断发现与番石榴相关的新药用特性,丰富了我们对其潜在益处的理解。版权所有 © 2023,Joshi 等人。
For centuries, herbal remedies have been employed to address a variety of human ailments, and Psidium guajava Linn (Myrtaceae), commonly known as guava, stands out as a noteworthy medicinal plant with significant pharmacological potential. In India, particularly in rural areas where access to conventional medicines can be limited, the various parts of the Psidium guajava plant, including its leaves, bark, roots, and fruit, have been harnessed for their therapeutic properties to tackle various health issues. Psidium guajava Linn proves to be a valuable repository of essential nutrients along with bioactive compounds such as α-terpineol, β-caryophyllene (trans-caryophyllene), rutin, α-humulene, oleanolic acid, flavonoids, and quercetin. These components exhibit diverse medicinal activities, encompassing anti-inflammatory, anti-cancer, anti-bronchitis, anti-proliferative, anti-tumor, anti-bacterial, and anti-diabetic effects. Every facet of the guava plant holds economic significance and is cultivated on a large scale. Taxonomically, Psidium guajava can be classified within the Plantae kingdom, Magnoliophyta division, Magnoliopsida class, Rosidae subclass, Myrtales order, Myrtaceae family, Myrtoideae subfamily, Myrteae tribe, Psidium genus, Guajava species. This adaptability of guava to various soils and environmental conditions facilitates relatively easy cultivation, yielding rapid fruit production. Its widespread cultivation across India is attributed to its manifold commercial applications. To comprehensively comprehend how this plant can effectively address the array of health challenges encountered by the Indian populace, this review delves into its multifaceted therapeutic properties, highlighting its significance in healthcare practices. Ongoing research endeavors by investigators continue to uncover novel medicinal attributes associated with Psidium guajava, enriching our understanding of its potential benefits.Copyright © 2023, Joshi et al.