实体器官移植后出现的恶性肿瘤的发病率正在增加，肿瘤学家也看到越来越多接受器官移植的患者。在本病例报告中，我们介绍了如何通过进行全面的图表审查并分析放射治疗计划软件 Eclipse 中的剂量测定，对肾移植患者安全地进行盆腔放射治疗。一名52岁的女性患者于2002年接受了肾移植，11年后被诊断出患有cT3 N0 M0肛管鳞状细胞癌。她接受了 25 次 45 Gy 的根治性放射治疗，使用体积调制弧形治疗计划对盆腔淋巴结和肿瘤进行治疗，然后使用三维适形放射治疗计划单独对肛门肿瘤进行 9 Gy 加强放射治疗，并同时进行 5 次放射治疗。 -氟尿嘧啶/丝裂霉素化疗总剂量为54 Gy。除了在肾脏周围创建 1 厘米的规划风险体积并使用半梁块之外，还对右侧髂外和腹股沟淋巴结的覆盖进行了妥协，以减少孤立盆腔肾的剂量。她的盆腔肾脏仅接受了 6.68 Gy 的平均剂量。八年后，该患者仍然没有癌症，最近 2021 年的乙状结肠镜检查和 2022 年的体检证明了这一点。她的肌酐在治疗一年后开始上升，但移植肾的年龄可能是导致癌症的原因。肾衰竭。版权所有 © 2023，Riopel 等人。

The incidence of malignancies seen after solid organ transplant is increasing, and oncologists are seeing more patients with transplanted organs. In this case report, we present how pelvic radiotherapy can be safely administered in a patient with a transplanted kidney by conducting a comprehensive chart review and analyzing the dosimetry in the radiotherapy planning software Eclipse. A 52-year-old female patient received a kidney transplant in 2002 and was diagnosed 11 years later with a cT3 N0 M0 squamous cell carcinoma of the anal canal. She was offered radical radiation therapy with 45 Gy in 25 fractions using a volumetric modulated arc therapy plan to the pelvic lymph nodes and tumor followed by a 9-Gy boost to the anal tumor alone using a three-dimensional conformal radiation therapy plan with concurrent 5-fluorouracil/mitomycin chemotherapy for a total dose of 54 Gy. The right external iliac and inguinal lymph nodes coverage was compromised to decrease the solitary pelvic kidney dose in addition to creating a 1-cm planning risk volume around the kidney and using half-beam blocks. Her pelvic kidney only received a mean dose of 6.68 Gy. Eight years later, the patient continues to be cancer-free, as evident with a recent sigmoidoscopy in 2021 and a physical examination in 2022. Her creatinine started to rise one year post-treatment, but age of the transplanted kidney is likely the cause of kidney failure.Copyright © 2023, Riopel et al.