亚洲国家阴道癌的生存率:系统评价和荟萃分析。
Survival rate of vaginal cancer in Asian countries: a systematic review and meta-analysis.
发表日期:2023 Nov
作者:
Mohebat Vali, Zahra Maleki, Mohammad-Ali Jahani, Maryam Hajizade-Valokolaee, Seyedeh Niko Hashemi, Saman Sedighi, Mousa Ghelichi-Ghojogh, Soheil Hassanipour, Arezo Solati, Mostafa Javanian, Hossein-Ali Nikbakht
来源:
TROPICAL MEDICINE & INTERNATIONAL HEALTH
摘要:
阴道癌是女性死亡的主要原因之一,主要发生在低收入和中等收入国家。评估阴道癌的存活率对于研究当前治疗和筛查工具的成功率至关重要。这项研究旨在确定亚洲阴道癌的生存率。这项系统评价是使用四个国际数据库进行的,包括 Medline/Pubmed、ProQuest、Scopus、Web of Knowledge 和 Google Scholar。文章调查截至 2021 年 8 月底。作者利用纽卡斯尔-渥太华量表来评估文章的质量。使用 Cochrane 检验和 I² 统计来评估论文的异质性。还根据研究年份应用荟萃回归分析。三篇文章(13 条记录)满足纳入标准。根据随机模型,总体5年生存率为74.63%。此外,与治疗类型(包括化疗、放疗或其他方式)相关的生存率分别为 78.53%、78.44% 和 68.54%。根据荟萃回归分析,未发现生存率与研究年份之间存在相关性。与发达国家相比,亚洲国家的阴道癌生存率较低。在这些国家,通过实施更新的诊断工具、先进的手术技术和目标导向的治疗来提高患者的生存率至关重要。较低阶段的早期诊断以及对人群进行风险因素和预防措施的教育对于提高生存率也是必要的。版权所有 © 2023 作者。由 Wolters Kluwer Health, Inc. 出版
Vaginal cancer is one of the major causes of mortality in women, which mostly takes place in low- and middle-income countries. Assessing the survival rate of vaginal cancer is essential to investigate the success rate of current treatments and screening tools. This study aims to determine the survival rate of vaginal cancer in Asia.This systematic review was carried out using four international databases, including Medline/Pubmed, ProQuest, Scopus, Web of Knowledge, and also Google Scholar. Articles were investigated up to the end of August 2021. The authors utilized the Newcastle-Ottawa Scale to evaluate the quality of the articles. Evaluating the papers for heterogeneity was performed using the Cochrane test and I² statistic. Meta-regression analysis was also applied based on the year of the study.Three articles (13 records) fulfilled the inclusion criteria. Based on the random model, the overall 5-year survival rate was 74.63%. Also, the rates of survival in relation to the type of treatment including chemotherapy, radiotherapy, or other modalities, were 78.53, 78.44, and 68.54%, respectively. According to meta-regression analysis, no correlation was found between the survival rate and the year of the study.The vaginal cancer survival rate is lower in Asian countries compared to that of developed countries. Increasing patient survival rates in such countries is crucial by implementing newer diagnostic tools, advanced surgical techniques, and goal-oriented treatments. Early diagnosis in lower stages and educating the populations about risk factors and preventative measures are also necessary for raising the rate of survival.Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.