由于不健康的现代生活方式，感染重大疾病的机会增加。白杨素是许多植物中的黄酮类黄酮类化合物，包括西番莲和天竺葵。白杨素长期以来被用来治疗多种疾病。白杨素是一种重要的黄酮类化合物，具有多种药理作用，包括抗癌、抗病毒、抗炎、抗关节炎、抗抑郁、降血脂、保肝和肾保护活性。本次探索性综述的目的是对黄酮类化合物进行全面综述，证实白杨素具有对肝脏和肾脏具有治疗潜力，并减少多种毒物引起的肝毒性和肾毒性，这有助于毒理学家、药理学家和化学家开发新的、含有白杨素和其他毒物的更安全的药品。 - 选择最适合所选主题的解释和内容。对所获得的信息进行分析，通过按标题、摘要和整个作品筛选来源来确定结果。作者们共同决定了要考虑的研究。必要的细节被系统地组织成标题和副标题，并进行了集中讨论。本综述中提供的信息是通过在多个在线平台上有针对性的搜索获得的，包括 Google Scholar、Scifinder、PubMed、Science Direct、ACS 出版物和 Wiley Online Library。这些作品是根据所有作者同意的纳入标准进行选择的。白杨素是一种有前途的生物活性黄酮类化合物，具有显着的健康益处，其合成替代品正被用作治疗各种疾病的药物。研究结果显示，白杨素通过降低肝毒性生物标志物水平和提高抗氧化剂水平，对多种肝毒物（如 2,3,7,8 四氯二苯并二恶英、四氯化碳 (CCl4)、顺铂等）具有保肝作用。此外，白杨素通过降低肾脏毒性标志物水平、减少氧化应激和提高抗氧化剂水平，对各种肾毒物（如顺铂、阿霉素、扑热息痛、庆大霉素、链霉唑嗪等）具有潜在的肾保护特性。根据这项修订后的研究，白杨素是一种有前途的植物成分，可用作引起肝毒性和肾毒性的各种药物的替代治疗。利用活性白杨素，可以配制多种针对肝脏和肾脏的剂型。版权所有© Bentham Science Publishers；如有任何疑问，请发送电子邮件至 epub@benthamscience.net。

The chance of contracting significant diseases increases due to an unhealthy and contemporary lifestyle. Chrysin is a flavonoid of the flavone class in numerous plants, including Passiflora and Pelargonium. Chrysin has long been used to treat a variety of illnesses. Chrysin, an essential flavonoid, has many pharmacological actions, including anticancer, antiviral, anti-inflammatory, anti-arthritic, depressive, hypolipidemic, hepatoprotective, and nephroprotective activity.This explorative review was commenced to provide a holistic review of flavonoids confirming that Chrysin has a therapeutic potential on the liver and kidney and reduces the hepatotoxicity and nephrotoxicity induced by diverse toxicants, which can be helpful for the toxicologists, pharmacologists, and chemists to develop new safer pharmaceutical products with chrysin and other toxicants.The most relevant studies that were well-explained and fit the chosen topic best were picked. The achieved information was analyzed to determine the outcome by screening sources by title, abstract, and whole work. Between themselves, the writers decided on the studies to be considered. The necessary details were systematically organized into titles and subtitles and compressively discussed.The information presented in this review is obtained using targeted searches on several online platforms, including Google Scholar, Scifinder, PubMed, Science Direct, ACS publications, and Wiley Online Library. The works were chosen based on the inclusion criteria agreed upon by all authors.Chrysin is a promising bioactive flavonoid with significant health benefits, and its synthetic replacements are being utilized as pharmaceuticals to treat various diseases. Findings revealed that Chrysin exhibits hepatoprotective actions against several hepatotoxicants like 2,3,7,8 tetrachlorodibenzo- p-dioxin, carbon tetrachloride (CCl4), cisplatin, and others by lowering the levels of liver toxicity biomarkers and enhancing antioxidant levels. Additionally, chrysin has potential nephroprotective properties against various nephrotoxicants, like Cisplatin, Doxorubicin, Paracetamol, Gentamicin, Streptazosin, and others by dropping kidney toxicity marker levels, reducing oxidative stress, and improving the antioxidant level.According to this revised study, chrysin is a promising phytoconstituent that can be utilized as an alternate treatment for various medications that cause hepatotoxicity and nephrotoxicity. With active chrysin, several dosage forms targeting the liver and kidneys can be formulated.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.