研究动态
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HPV疫苗接种时代中国女性宫颈筛查:基于18年有组织筛查计划的筛查接受率和定期筛查的人群调查。

Cervical screening among Chinese females in the era of HPV vaccination: a population-based survey on screening uptake and regular screening following an 18-year organized screening program.

发表日期:2023 Oct 18
作者: Horace Cw Choi, Kathy Leung, Joseph T Wu
来源: Journal of Gynecologic Oncology

摘要:

中国的宫颈癌疾病负担沉重。为了进一步了解中国减少宫颈癌的预防措施,本研究旨在将中国女性的筛查出勤率和定期筛查与人乳头瘤病毒(HPV)疫苗接种联系起来。这项前瞻性问卷调查招募了25岁或以上在香港的中国女性,通过以下方式进行: 2022 年随机数字拨号电话访谈。该调查研究了女性宫颈筛查的实践以及定期筛查的坚持情况。问卷中涉及的变量包括HPV疫苗接种状况和体检参加情况。筛查率和筛查依从性是主要结果,分别以报告参加过宫颈筛查和定期筛查的女性比例来衡量。在 906 名有效受访者中,报告的 30 岁女性宫颈筛查率超过 70%或以上,特别是 35-59 岁女性中超过 80%;然而,25-29 岁人群的使用率仅为 46%。 25-59 岁女性坚持定期筛查的比例为 50%-60%,而 60 岁以上女性的比例下降至约 40%。筛查的接受率和依从性均与 HPV 疫苗接种相关,调整后的比值比分别为 2.37 和 2.23。很大一部分定期筛查的女性可能会过度筛查,筛查频率可能高于建议的频率。受访的中国女性表现出良好的宫颈筛查率,但对定期筛查的坚持程度中等。政策制定者应强调定期筛查的重要性以及根据 HPV 疫苗接种状况推荐的筛查频率,以更好地利用医疗资源。© 2024。亚洲妇科肿瘤学会、韩国妇科肿瘤学会和日本妇科肿瘤学会。
China has a substantial disease burden of cervical cancer. To further understand preventive measures for reducing cervical cancer in China, this study aimed to correlate screening attendance and regular screening with human papillomavirus (HPV) vaccination among Chinese females.This prospective questionnaire-based survey recruited Chinese females aged 25 or above in Hong Kong by random digit dialing telephone interviews in 2022. The survey studied women's practice of cervical screening and adherence to regular screening. Variables including HPV vaccination status and attendance of physical check-ups were involved in the questionnaire. Screening uptake and screening adherence were the main outcomes, which were measured as the proportion of women who reported having attended a cervical screening and screened regularly, respectively.Out of 906 valid respondents, the reported cervical screening uptake was over 70% among females aged 30 or above and particularly over 80% among women aged 35-59; however, the uptake was only 46% among those aged 25-29. Adherence to regular screening was 50%-60% across ages 25-59 years and dropped to approximately 40% for women older than 60 years. Both screening uptake and adherence were associated with HPV vaccination, with adjusted odds ratios of 2.37 and 2.23, respectively. A large proportion of regularly screened women may be overscreened for screening more frequently than recommended.Responded Chinese females showed good cervical screening uptake but were moderately adherent to regular screening. Policymakers should emphasize the importance of regular screening and the recommended screening frequency by HPV vaccination status for better healthcare resource use.© 2024. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology, and Japan Society of Gynecologic Oncology.