本研究旨在系统地探讨体育锻炼作为头颈癌支持疗法的影响。对 PubMed/MEDLINE、Cochrane 和 SPORTDiscus 进行了系统检索。选择了随机对照试验，探讨体育锻炼干预与常规护理相比对头颈癌患者预后的影响。 RoB 2 工具用于确定研究质量。提取的数据以定性综合报告。在检查的 527 条记录中，纳入了 9 项研究。没有发现将运动作为康复前研究的试验，而涉及 452 名头颈癌患者的 8 项研究是在抗癌治疗期间进行的。大多数试验没有报告体重指数或身体成分的改善，而 2/4 和 3/5 的研究分别发现肌肉力量和心肺健康显着增加。关于患者报告的结果，七分之四的研究观察到生活质量某些领域的改善，三分之二的试验检测到运动干预后疲劳得到改善。从运动项目分析来看，有氧运动和抗阻训练相结合似乎比单一的全身运动更有利于抗癌治疗阶段的体力衰退和控制症状。一项试验调查了抗阻运动对终止抗癌治疗的患者的影响，报告显示瘦体重、肌肉力量和生活质量显着改善。对于头颈癌患者来说，运动可能是一种有前景的方法。需要进一步的研究来巩固这些结果。© 2023。作者。

This study aims to systematically explore the impact of physical exercise as supportive therapy for head and neck cancer.A systematic search on PubMed/MEDLINE, Cochrane, and SPORTDiscus was conducted. Randomized controlled trials exploring the effects of a physical exercise intervention in comparison with usual care on outcomes in patients with head and neck cancer were selected. The RoB 2 tool was used to determine the study quality. The extracted data are reported as qualitative synthesis.Among the 527 records examined, nine studies were included. No trials investigating exercise as prehabilitation were found, whereas eight studies involving 452 patients with head and neck cancer were conducted during anticancer treatment. Most trials did not report improvements in body mass index or body composition, while 2/4 and 3/5 investigations found a significant increase in muscle strength and cardiorespiratory fitness, respectively. Regarding the patients' reported outcomes, 4 out of 7 studies observed enhancements in some domains of quality of life, and two trials out of 3 detected an amelioration in fatigue following the exercise intervention. Analyzing the exercise programs, it seems that combining aerobic and resistance training could be more beneficial compared to a single type of full-body exercise in counteracting physical decline and controlling symptoms in the anticancer therapy phase. One trial has investigated the effect of resistance exercise on patients who had terminated the anticancer treatments, reporting significant improvements in lean mass, muscle strength, and quality of life.Exercise may be a promising approach in patients with head and neck cancer. Future studies are needed to consolidate these results.© 2023. The Author(s).