遵守肺癌筛查 (LCS) 方案对于降低死亡率至关重要。然而，依从率，特别是对于低风险患者中推荐的年度筛查的依从率，通常不是最佳的。我们评估了参与三级学术中心集中筛查计划的低风险患者的年度 LCS 依从性。我们对 2018 年 7 月启动的集中肺癌筛查计划进行了回顾性、观察性队列研究。我们对337 名患者在 2021 年 2 月 1 日之前接受了低剂量 CT (LDCT) 筛查（以确保≥ 15 个月的随访），且低风险 Lung-RADS 评分为 1 或 2。捕获的数据包括患者特征（吸烟史、 Fagerstrom 评分、环境暴露、肺癌风险评分）、LDCT 成像日期和 Lung-RADS 结果。主要结果指标是遵守年度筛查。我们使用多变量逻辑回归模型来确定与依从性相关的因素。总体而言，337 名患者的初始 Lung-RADS 结果为 1 (n = 189) 或 2 (n = 148)。在该队列中，139 名 (73.5%) 的 Lung-RADS 1 患者和 111 名 (75.0%) 的 Lung-RADS 2 患者在 15 个月内分别完成了年度重复 LDCT。与依从性相关的唯一患者特征是有医疗补助覆盖；与拥有私人保险相比，医疗补助患者的依从性较低（调整后 OR = 0.37，95% CI = 0.15-0.92）。没有其他患者特征与依从性相关。我们的集中筛查计划实现了较高的初始年依从率。尽管 LCS 拥有第一美元的保险范围，但其他社会经济问题可能会对医疗补助受益人的年度筛查构成障碍。版权所有 © 2023 Elsevier Inc. 保留所有权利。

Adherence to lung cancer screening (LCS) protocols is critical for achieving mortality reductions. However, adherence rates, particularly for recommended annual screening among patients with low-risk findings, are often sub-optimal. We evaluated annual LCS adherence for patients with low-risk findings participating in a centralized screening program at a tertiary academic center.We conducted a retrospective, observational cohort study of a centralized lung cancer screening program launched in July 2018. We performed electronic medical review of 337 patients who underwent low-dose CT (LDCT) screening before February 1, 2021 (to ensure ≥ 15 months follow up) and had a low-risk Lung-RADS score of 1 or 2. Captured data included patient characteristics (smoking history, Fagerstrom score, environmental exposures, lung cancer risk score), LDCT imaging dates, and Lung-RADS results. The primary outcome measure was adherence to annual screening. We used multivariable logistic regression models to identify factors associated with adherence.Overall, 337 patients had an initial Lung-RADS result of 1 (n = 189) or 2 (n = 148). Among this cohort, 139 (73.5%) of Lung-RADS 1 and 111 (75.0%) of Lung-RADS 2 patients completed the annual repeat LDCT within 15 months, respectively. The only patient characteristic associated with adherence was having Medicaid coverage; compared to having private insurance, Medicaid patients were less adherent (adjusted OR = 0.37, 95% CI = 0.15-0.92). No other patient characteristic was associated with adherence.Our centralized screening program achieved a high initial annual adherence rate. Although LCS has first-dollar insurance coverage, other socioeconomic concerns may present barriers to annual screening for Medicaid recipients.Copyright © 2023 Elsevier Inc. All rights reserved.