根据高分辨率计算机断层扫描的结果，原发性肺粘液腺癌（LMA）可分为纯实性型、部分实性型和肺炎型。本研究旨在基于大量患者的放射学分类，阐述 LMA 的临床病理学、放射学和预后特征。从 2009 年 11 月至 2016 年 12 月，本研究入组了 294 例切除的 LMA，分为纯实性（纯实性）、 n = 169)、部分实体型 (n = 87) 和肺炎型 (n = 38)。评估肿瘤的临床病理学和放射学特征，并通过随访评估确定患者预后。通过卡普兰-迈耶曲线计算生存结果，并使用对数秩检验进行比较。通过建立 Cox 比例风险模型来评估临床病理变量（包括放射学表现）的预后影响。LMAs 很少与淋巴结转移 (5.4%)、淋巴管/血管侵犯 (4.4%) 或内脏胸膜侵犯 (5.1%) 相关。 %）。在中位 71 个月的随访期内，62 名患者出现复发，44 名患者死亡。肺炎型 LMA 患者的预后（5 年无复发生存率 [RFS]，23.7%；5 年总生存率 [OS]，44.7%）比纯实体型患者（RFS，83.2%）较差。 %；OS，100 %）或部分固体型（RFS，93.7 %；OS，100 %）。此外，淋巴结转移、肺气肿和临床T分期是RFS和OS的独立预测因素。孤立型LMA患者预后良好，而肺炎型LMA患者的生存结果较差。此外，肺炎型 LMA 患者更容易通过气道播散而非远处转移发生肺内转移。© 2023。外科肿瘤学会。

Primary lung mucinous adenocarcinomas (LMAs) could be subclassified as the pure-solid, part-solid, and pneumonic types according to the findings of high-resolution computed tomography. This study aimed to expound on the clinicopathologic, radiologic, and prognostic characteristics of LMAs based on radiologic classification within a large set of patients.From November 2009 to December 2016, this study enrolled 294 resected LMAs, which were divided into the pure-solid (n = 169), part-solid (n = 87), and pneumonic (n = 38) types. The clinicopathologic and radiologic characteristics of the tumors were evaluated, and patient prognosis was determined through follow-up evaluation. Survival outcomes were calculated by Kaplan-Meier curves and compared using log-rank tests. The prognostic impact of clinicopathologic variables, including radiologic presentations, were evaluated by establishing a Cox proportional hazards model.The LMAs were infrequently associated with lymph node metastasis (5.4 %), lymphatic/vascular invasion (4.4 %), or visceral pleural invasion (5.1 %). During the median 71-month follow-up period, recurrence was observed in 62 patients and death in 44 patients. The patients with pneumonic-type LMAs had a poorer prognosis (5-year recurrence-free survival [RFS], 23.7 %; 5-year overall survival [OS], 44.7 %) than those with the pure-solid type (RFS, 83.2 %; OS, 100 %) or part-solid type (RFS, 93.7 %; OS, 100 %). Besides, lymph node metastasis, emphysema, and clinical T stage were independent predictors of RFS and OS.Solitary-type LMA patients had excellent prognoses, whereas the survival outcomes for pneumonic-type LMA patients were dismal. Furthermore, pneumonic-type LMA patients were prone to intrapulmonary metastasis by means of aerogenous dissemination rather than distant metastasis.© 2023. Society of Surgical Oncology.