蝶眶脑膜瘤起源于蝶骨嵴处的蛛网膜绒毛帽细胞，并具有通过软组织延伸和颅骨侵入而扩散的能力。由于眼眶骨质增生和眼眶内软组织延伸，它们通常出现眼科表现。本研究旨在探讨肿瘤体积与症状和术后结果之间的相关性。这项回顾性研究分析了接受蝶眼眶脑膜瘤手术切除的患者。使用术前和术后成像测量不同区室中的肿瘤体积。使用线性和逻辑回归分析来确定肿瘤体积与术前症状和术后结果之间的相关性。本研究纳入了 66 名患者，其中 86.4% 患有眼球突出，80.3% 视力下降（VA），30.3%有视野缺损，13.6%有眶周水肿。术前，突眼与骨内肿瘤体积呈线性相关（系数 = 0.6，P < .001），而基线 VA 的降低与眼眶内肿瘤体积相关（系数 = 0.3，P = .01）。发现眶周水肿的几率随着骨内肿瘤体积的增加而增加，调整后的比值比为 1.4（95% CI，1.1-1.7，P = .003），而视野缺损的几率随着骨内肿瘤体积的增加而增加。眶内肿瘤体积增加，调整后的优势比为 2.7（95% CI，1.3-5.6，P = .01）。术后，骨内肿瘤切除的体积与眼球突出的改善呈线性相关（系数 = 0.7，P < .001），而眶内肿瘤切除的体积与 VA 的改善呈线性相关（系数 = 0.5，P < .001）和对于术前 VA 中度至重度下降的患者，效果更大（系数 = 0.8）。强调每个肿瘤区室相对于患者症状的重要性，可以作为实施针对不同肿瘤的区室化切除方法的宝贵指南。手术目标。版权所有 © 神经外科医生大会 2023。保留所有权利。

Spheno-orbital meningiomas arise from the arachnoid villi cap cells at the sphenoid ridge and have the ability to spread through soft tissue extension and cranial bone invasion. Owing to their orbital hyperostosis and intraorbital soft tissue extension, they commonly present with ophthalmologic manifestations. This study aims to investigate the correlation between tumor volume with the presenting symptoms and postoperative outcomes.This retrospective study analyzed patients who underwent surgical resection of spheno-orbital meningiomas. Tumor volumes in different compartments were measured using preoperative and postoperative imaging. Linear and logistic regression analyses were used to identify correlations between tumor volumes and presenting symptoms preoperatively and postoperative outcomes.Sixty-six patients were included in this study, of whom 86.4% had proptosis, 80.3% had decreased visual acuity (VA), 30.3% had visual field defects, and 13.6% had periorbital edema. Preoperatively, proptosis linearly correlated with intraosseous tumor volume (coefficient = 0.6, P < .001), while the decrease in baseline VA correlated with the intraorbital tumor volume (coefficient = 0.3, P = .01). The odds of periorbital edema were found to increase with an increase in intraosseous tumor volume with an adjusted odds ratio of 1.4 (95% CI, 1.1-1.7, P = .003), while the odds of visual field defects were found to increase with an increase in intraorbital tumor volume with an adjusted odds ratio of 2.7 (95% CI, 1.3-5.6, P = .01). Postoperatively, the volume of intraosseous tumor resected linearly correlated with the improvement in proptosis (coefficient = 0.7, P < .001), while the volume of intraorbital tumor resected linearly correlated with improvement in VA (coefficient = 0.5, P < .001) and with a larger effect size in patients presenting with moderate-to-severe decrease in VA preoperatively (coefficient = 0.8).Underscoring the importance of each tumor compartment relative to the patient's symptomatology serves as a valuable guide in implementing a compartmentalized resection approach tailored to the surgical objectives.Copyright © Congress of Neurological Surgeons 2023. All rights reserved.