SARS-CoV-2 大流行对英格兰肺癌生存的影响:快速癌症登记数据集的分析。
Impact of the SARS-CoV-2 pandemic on lung cancer survival in England: an analysis of the rapid cancer registration dataset.
发表日期:2023 Nov 06
作者:
Helen Morgan, Savannah Gysling, Neal Navani, David Baldwin, Richard Hubbard, Emma O'Dowd
来源:
THORAX
摘要:
肺癌治疗的早期改变可能会影响生存。鉴于封锁期间诊断率的下降,我们使用国家肺癌审计数据计算了其对生存的影响。对 2019 年和 2020 年封锁期间的生存百分比和死亡 HR 进行了比较。从第一次全国封锁开始以及诊断后 90 天内,观察到生存率下降。 2020 年底诊断的患者在 90 天内死亡的 HR 最高,为 1.26(95% CI 1.20 至 1.32),在 91 至 270 天内死亡的 HR 为 1.51(95% CI 1.42 至 1.60)。需要进一步研究减轻这种影响的措施。© 作者(或其雇主)2023。禁止商业重复使用。请参阅权利和权限。由英国医学杂志出版。
Early changes in lung cancer care can affect survival. Given the decrease in diagnosis during lockdowns, we calculated their impact on survival using National Lung Cancer Audit data. Percentage survival and HRs for death were compared between 2019 and lockdown periods of 2020. Decreased survival was observed from the first national lockdown onwards and within 90 days of diagnosis. HRs were highest for people diagnosed at the end of 2020 at 1.26 (95% CI 1.20 to 1.32) for death within 90 days and 1.51 (95% CI 1.42 to 1.60) for death between 91 and 270 days. Further work is needed on measures to mitigate this impact.© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.