研究动态
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腹腔镜远端胃切除术后体内三角型胃十二指肠吻合术和胃空肠吻合术之间的长期功能和患者报告的结果。

Long-term Functional and Patient-reported Outcomes Between Intra-corporeal Delta-shaped Gastroduodenostomy and Gastrojejunostomy After Laparoscopic Distal Gastrectomy.

发表日期:2023 Oct
作者: Sin Hye Park, Hong Man Yoon, Keun Won Ryu, Young-Woo Kim, Mira Han, Bang Wool Eom
来源: Food & Function

摘要:

本研究旨在比较腹腔镜胃癌远端胃切除术后体内三角型胃十二指肠吻合术和胃空肠吻合术的长期功能和患者报告的结果。我们回顾性分析了 616 例接受 I 期腹腔镜远端胃切除术的患者的临床病理数据。 2015年1月至2020年9月期间的胃癌患者。其中,232例接受三角吻合的患者和另外232例接受Billroth II吻合的患者使用倾向评分进行匹配。混杂变量包括年龄、性别、体重指数、身体状况分类、肿瘤位置和 T 分类。比较两组的术后并发症、营养结局、内镜检查结果和生活质量(QoL)。两组术后并发症或营养参数无显着差异。每年的内窥镜检查结果显示,与 Billroth II 组相比,Delta 组有更多的残留食物和更少的胆汁反流(P<0.001)。情绪功能、失眠、腹泻、反流症状和口干方面的生活质量变化存在显着差异(分别为P=0.007、P=0.002、P=0.013、P=0.001和P=0.03)。其中,Delta组术后三个月内失眠、反流症状和口干症状更严重。Delta组和Billroth II组的长期营养结果和生活质量相当。然而,在 Delta 组中观察到更多的残留食物和较差的短期生活质量(如失眠、反流症状和口干)。在内窥镜评估和短期症状管理之前延长禁食时间对 Delta 组会有所帮助。版权所有 © 2023。韩国胃癌协会。
This study aimed to compare the long-term functional and patient-reported outcomes between intra-corporeal delta-shaped gastroduodenostomy and gastrojejunostomy after laparoscopic distal gastrectomy for gastric cancer.We retrospectively reviewed clinicopathological data from 616 patients who had undergone laparoscopic distal gastrectomy for stage I gastric cancer between January 2015 and September 2020. Among them, 232 patients who had undergone delta-shaped anastomosis and another 232 who had undergone Billroth II anastomosis were matched using propensity scores. Confounding variables included age, sex, body mass index, physical status classification, tumor location, and T classification. Postoperative complications, nutritional outcomes, endoscopic findings, and quality of life (QoL) were compared between the 2 groups.No significant differences in postoperative complications or nutritional parameters between the two groups were observed. Annual endoscopic findings revealed more residual food and less bile reflux in the delta group (P<0.001) than in the Billroth II group. Changes of QoL were significantly different regarding emotional function, insomnia, diarrhea, reflux symptoms, and dry mouth (P=0.007, P=0.002, P=0.013, P=0.001, and P=0.03, respectively). Among them, the delta group had worse insomnia, reflux symptoms, and dry mouth within three months postoperatively.Long-term nutritional outcomes and QoL were comparable between the delta and Billroth II groups. However, more residual food and worse short-term QoL regarding insomnia, reflux symptoms, and dry mouth were observed in the delta group. Longer fasting time before endoscopic evaluation and short-term symptom management would have been helpful for the delta group.Copyright © 2023. Korean Gastric Cancer Association.