泌尿系统癌症，包括前列腺癌、肾癌和膀胱癌，是全世界范围内困扰人类的疾病。目前治疗这些癌症的策略是化疗、放疗、手术或上述疗法的组合。由于泌尿系统癌症的高死亡率和发病率以及现有标准治疗可能存在的副作用，寻找更有效和安全的治疗方法是一个关键问题。小檗碱等天然化合物的有益特性已在人类疾病中得到广泛研究。此外，这种药物的抗癌潜力已被广泛记录，特别是在实验研究中。在这篇综述中，我们试图讨论小檗碱对抗泌尿系癌症的作用，重点关注细胞和分子机制。版权所有© Bentham Science Publishers；如有任何疑问，请发送电子邮件至 epub@benthamscience.net。

Urological cancers, including prostate, kidney, and bladder cancer are problematic human diseases worldwide. Current strategies for the treatment of these cancers are chemotherapy, radiotherapy, surgery, or a combination of mentioned therapies. Due to the high mortality and morbidity rate of urological cancers and possible side effects of available standard treatments, searching for more effective and safe treatments is a critical issue. The beneficial properties of natural compounds, such as berberine, have been widely investigated in human diseases. Moreover, the anticancer potential of this agent has been extensively documented, especially in experimental studies. In this review, we have tried to discuss the effect of berberine against urological cancers, focusing on cellular and molecular mechanisms.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.