每年，HPV 感染会导致 7.75 亿美元的直接医疗费用和约 46 万例 HPV 相关癌症新病例。自 2006 年以来，已有安全、高效的疫苗用于儿童/青少年预防 HPV。疫苗接种率仍然很低，特别是在农村地区。父母的态度和信念影响 HPV 疫苗接种率。我们开发、测试和实施了一项调查，询问父母和医疗保健提供者在对符合年龄条件的儿童进行医疗保健就诊后如何就 HPV 疫苗进行互动，这是设计的多组分随机对照试验的一部分提高俄勒冈州农村地区的 HPV 疫苗接种率。这项21项调查评估了父母的信息寻求行为、HPV癌症风险降低知识、HPV疫苗系列以及他们的疫苗信心。43名参与者（59.7%）属于干预组；43名参与者（59.7%）属于干预组； 29 名（40.3%）为对照。超过 90% 的医疗就诊涉及疾病、受伤、体育锻炼或儿童健康就诊（n = 67 或 93.1%），6.9% 的就诊是针对疫苗的。研究组之间的医疗就诊没有发现统计学上的显着差异。超过一半的父母表示与他们的护理人员讨论过 HPV 和 HPV 疫苗 (54.5%)，31.3% 的父母最近在就诊前了解了 HPV、HPV 风险和 HPV 疫苗，83.1% 的父母了解与 HPV 相关的癌症HPV，79.2% 正在考虑为他们的孩子接种疫苗，这在研究组之间没有差异。有关 HPV 相关癌症的知识和考虑给儿童接种疫苗的知识高于预期，但与测试的干预措施无关。

Annually, HPV infections result in $775 million in direct medical costs and approximately 46 000 new cases of HPV-associated cancers. Safe and highly effective vaccines have been available to prevent HPV for children/adolescents since 2006. Vaccination rates remain low, especially in rural areas. Parental attitudes and beliefs affect HPV vaccination rates.We developed, tested, and administered a survey that asked how parents and healthcare providers interacted about the HPV vaccine following a healthcare visit with an age-eligible child, as part of a multicomponent randomized controlled trial designed to improve HPV vaccination rates in rural Oregon. The 21-item survey assessed parents' information-seeking behavior, knowledge about HPV cancer risk reduction, the HPV vaccine series, and their vaccine confidence.Forty-three participants (59.7%) were in the intervention group; 29 (40.3%) were controls. Over 90% of healthcare visits were illness, injury, sports physical, or well-child visits (n = 67 or 93.1%), and 6.9% of visits were vaccine-specific. No statistically significant differences were found between study groups for healthcare visits. Over half the parents reported having discussions about HPV and the HPV vaccine (54.5%) with their care providers, 31.3% had recently learned about HPV, HPV risks, and the HPV vaccine prior to the visit, 83.1% were knowledgeable about cancers associated with HPV, and 79.2% were considering vaccinating their child(ren), which did not differ between study groups.Knowledge about HPV-related cancers and consideration for vaccinating children was higher than expected, but not associated with the intervention tested.