患有可疑皮肤癌病变的患者经常就诊于初级保健医生 (PCP)，他们在皮肤癌诊断方面的培训可能有限。旨在衡量采用弹性散射光谱 (ESS) 的 PCP 辅助手持设备对诊断和诊断的影响57 名 PCP 评估了 50 幅皮肤病变的临床图像（25 幅是恶性的，25 幅是良性的），先是在不了解手持式 ESS 设备输出的情况下进行评估，然后在了解手持式 ESS 设备输出的情况下进行评估，并在每种情况下都指出病变是否可能是良性的使用和不使用 ESS 装置的 PCP 的诊断敏感性分别为 88%（95% CI，84%-92%）和 67%（95% CI，62%-72%）（P < .0001)。相反，诊断特异性没有观察到显着差异。使用和不使用 ESS 装置的医生的管理敏感性分别为 94% (95% CI, 91%-96%) 和 81% (95% CI, 77%-85%) (P = .0009 ）。同样，在管理特异性方面也没有观察到显着差异。使用 ESS 设备可能有助于改善初级保健环境中皮肤癌的诊断和管理决策的信心。

Patients with lesions suspicious for skin cancer often present to primary care physicians (PCPs), who may have limited training in skin cancer diagnosis.To measure the impact of an adjunctive handheld device for PCPs that employs elastic scattering spectroscopy (ESS) on the diagnosis and management of skin cancer.Fifty-seven PCPs evaluated 50 clinical images of skin lesions (25 malignant and 25 benign), first without and then with knowledge of the handheld ESS device output, and in each case indicated if a lesion was likely to be benign or malignant.The diagnostic sensitivity of the PCPs with and without the use of the ESS device was 88% (95% CI, 84%-92%) and 67% (95% CI, 62%-72%), respectively (P < .0001). In contrast, no significant difference was observed in the diagnostic specificity. The management sensitivity of the physicians with and without the use of the ESS device was 94% (95% CI, 91%-96%) and 81% (95% CI, 77%-85%), respectively (P = .0009). Similarly, no significant difference was observed in the management specificity.The use of the ESS device may have the potential to help improve skin cancer diagnosis and confidence in management decision-making in a primary care setting.