软骨母细胞瘤骨转移:成人中一种罕见的转移性疾病。
Bone metastases from chondroblastoma: a rare pattern of metastatic disease in an adult.
发表日期:2023 Nov 07
作者:
Jennifer Murphy, Anish Patel, Simon Hughes, Petr Rehousek, John Drake, Vaiyapuri Sumathi, Rajesh Botchu, A Mark Davies
来源:
Bone & Joint Journal
摘要:
软骨母细胞瘤是一种罕见的良性肿瘤,通常在前二十年出现。软骨母细胞瘤的全身转移极为罕见,正是这些转移的罕见性导致世界卫生组织在 2020 年更新的骨肿瘤分类中将这种病变从“中间”重新分类为“良性”。我们介绍一个常见病例一名 55 岁男性患者,11 年前在另一家机构切除的传统肋骨软骨母细胞瘤背景下,出现多处 FDG 亲和性骨病变。其中两个病变在活检时也被组织学证明为传统软骨母细胞瘤。该病例强调,尽管罕见,但在软骨母细胞瘤患者中仍可看到转移。据我们所知,这是唯一一个具有仅限于骨骼的不寻常转移模式的病例。© 2023。作者,获得国际骨骼协会 (ISS) 的独家许可。
Chondroblastoma is a rare benign tumor, typically presenting in the first two decades. Systemic metastases in chondroblastoma are extremely rare and it is the rarity of these metastases which lead the World Health Organisation to re-classify this lesion from "intermediate" to "benign" in its updated classification of bone tumors in 2020. We present an usual case of a 55 year-old male patient who presented with multiple FDG-avid bone lesions on a background of conventional chondroblastoma of the rib excised at another institution 11-years previously. Two of these lesions were also histologically-proven as conventional chondroblastoma at biopsy. This case highlights that, although rare, metastases can be seen in patients with chondroblastoma. To our knowledge, this is the only case with an unusual pattern of metastases limited to bone.© 2023. The Author(s), under exclusive licence to International Skeletal Society (ISS).