骨盆转移性骨病的治疗:当前概念。
Management of metastatic bone disease of the pelvis: current concepts.
发表日期:2023 Nov 07
作者:
Hüseyin Bilgehan Çevik, Pietro Ruggieri, Peter V Giannoudis
来源:
Bone & Joint Journal
摘要:
骨盆转移性疾病常常与剧烈疼痛和行走功能受损有关。根据患者的特征、原发肿瘤和转移性盆腔疾病,治疗选择可能会有所不同。本研究旨在报告转移性骨盆疾病的当前治疗选择。我们全面研究了多个数据库,并评估了有关治疗骨盆转移性骨疾病的当前概念的基本研究,重点关注具体适应症和治疗结果。不在髋臼周围区域的骨盆转移可以通过改变负重、镇痛药、双磷酸盐、化疗和/或放疗来治疗。微创方法包括射频消融、冷冻消融、栓塞、经皮骨成形术和经皮螺钉置入术。病理性或即将发生的髋臼周围骨折、髋臼周围骨缺损过多、放射抗性肿瘤以及尽管非手术治疗和/或微创手术仍持续的衰弱性疼痛可以通过不同的手术技术进行治疗。总体而言,根据具体适应症、患者的期望和病变情况,治疗可分为非手术治疗、微创治疗和手术治疗。转移性盆腔骨疾病有不同的治疗方式。应根据具体情况采用多学科方法做出最合适治疗的决策。© 2023。作者获得德国 Springer-Verlag GmbH 的独家许可。
Metastatic disease of the pelvis is frequently associated with severe pain and impaired ambulatory function. Depending on the patient's characteristics, primary tumor, and metastatic pelvic disease, the treatment choice may be varied. This study aims to report on the current management options of metastatic pelvic disease.We comprehensively researched multiple databases and evaluated essential studies about current concepts of managing a metastatic bone disease of the pelvis, focusing on specific indications as well as on the result of treatment.Pelvic metastases not in the periacetabular region can be managed with modification of weight-bearing, analgesics, bisphosphonates, chemotherapy and/or radiotherapy. Minimally invasive approaches include radiofrequency ablation, cryoablation, embolization, percutaneous osteoplasty, and percutaneous screw placement. Pathological or impending periacetabular fracture, excessive periacetabular bone defect, radioresistant tumor, and persistent debilitating pain despite non-surgical treatment and/or minimally invasive procedures can be managed with different surgical techniques. Overall, treatment can be divided into nonoperative, minimally invasive, and operative based on specific indications, the expectations of the patient and the lesion.Different treatment modalities exist to manage metastatic pelvic bone disease. Decision-making for the most appropriate treatment should be made with a multidisciplinary approach based on a case-by-case basis.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.