68Ga-PSMA-11（68Ga-前列腺特异性膜抗原-11）PET/CT 对于前列腺癌分期仍然具有巨大的临床价值。淋巴结和骨是前列腺癌最典型的转移部位，而肝转移很少见，并且通常在 68Ga-PSMA-11 PET/CT 中显示局灶性示踪剂摄取增加。在这里，我们介绍了一名 88 岁男性，其患有经组织学证实的转移性去势抵抗性前列腺癌，并通过 68Ga-PSMA-11 PET/CT 发现广泛的 PSMA 阴性肝转移。这一发现非常引人注目，因为 68Ga-PSMA-11 的肝脏摄取减少可能类似于原发性肝肿瘤。版权所有 © 2023 Wolters Kluwer Health, Inc. 保留所有权利。

68Ga-PSMA-11 (68Ga-prostate-specific membrane antigen-11) PET/CT continues to have a great clinical value for staging in prostate cancer. Lymph nodes and bone are the most typical metastatic sites of prostate cancer, whereas liver metastases are rare and usually show focally increased tracer uptake in 68Ga-PSMA-11 PET/CT. Here, we present an 88-year-old man with histologically proven metastatic castration-resistant prostate cancer and extensive PSMA-negative liver metastases identified by 68Ga-PSMA-11 PET/CT. This finding is remarkable because the decreased liver uptake of 68Ga-PSMA-11 may resemble a primary hepatic tumor.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.