本次系统评价和荟萃分析的目的是汇编关于 NLR 在预测子宫内膜异位症中的重要性的现有证据，以帮助临床决策和结果。我们检索了 ProQuest、Web of Science 和 PubMed 之前发表的相关研究2023 年 1 月 2 日。每个结果均报告了具有 95% 置信区间 (CI) 的标准化平均差 (SMD)。由于发现了显着的异质性，我们使用随机效应模型来计算汇总效应。我们使用纽卡斯尔-渥太华量表（NOS）进行质量评估。总体而言，分析中纳入了 18 篇文章。随机效应模型显示，与健康对照相比，子宫内膜异位症患者的 NLR 水平升高（SMD = 0.79，95% CI = 0.33 至 1.25，P < 0.001）。与其他良性肿瘤患者相比，子宫内膜异位症患者的NLR水平升高（SMD = 0.85，95% CI = 0.17至1.53，P = 0.014）。此外，III、IV期子宫内膜异位症患者的NLR水平与I、II期子宫内膜异位症患者无差异（SMD = 0.30，95%CI = -0.14～0.74，P = 0.18）。然而，有和无腹膜病变的子宫内膜异位症患者之间（SMD = -0.12，95% CI = -0.34至0.10，P = 0.28）、有和无子宫内膜异位症患者之间（SMD = 0.20，95% CI = -0.15至0.55，P = 0.26）以及有和无深部病变的子宫内膜异位症患者之间的差异（SMD = 0.04，95% CI = -0.20至0.28，P = 0.72）。 NLR 的汇总敏感性为 0.67（95% CI= 0.60-0.73），汇总特异性为 0.68（95% CI，0.62-0.73）。NLR 可在临床中用作可能的预测因子，帮助临床医生诊断受影响的子宫内膜异位症。女性。© 2023。作者。

The purpose of this systematic review and meta-analysis was to compile existing evidence on the significance of the NLR in predicting endometriosis in order to aid clinical decision-making and outcomes.We searched ProQuest, Web of Science, and PubMed for related studies published before January 2, 2023. Standardized mean difference (SMD) with a 95% confidence interval (CI) was reported for each outcome. Because a significant level of heterogeneity was found, we used the random-effects model to calculate pooled effects. We used Newcastle-Ottawa Scale (NOS) for quality assessment.Overall, 18 article with were included in the analysis. A random-effect model revealed that patients with endometriosis had elevated levels of NLR compared to healthy controls (SMD = 0.79, 95% CI = 0.33 to 1.25, P < 0.001). Patients with endometriosis had elevated levels of NLR compared to those with other benign tumors (SMD = 0.85, 95% CI = 0.17 to 1.53, P = 0.014). In addition, NLR level of patients with stage III and IV endometriosis was not different from that of patients with stage I and II endometrioma (SMD = 0.30, 95% CI = -0.14 to 0.74, P = 0.18). However, NLR level was not different between endometriosis patients with and without peritoneal lesions (SMD = -0.12, 95% CI = -0.34to 0.10, P = 0.28), between patients with and without endometrioma (SMD = 0.20, 95% CI = -0.15 to 0.55, P = 0.26) and between endometriosis patients with and without deep lesions (SMD = 0.04, 95% CI = -0.20 to 0.28, P = 0.72). The pooled sensitivity of NLR was 0.67 (95% CI = 0.60-0.73), and the pooled specificity was 0.68 (95% CI, 0.62-0.73).NLR might be utilized in clinics as a possible predictor to help clinicians diagnose endometriosis in affected women.© 2023. The Author(s).