桡动脉波用于乳腺癌患者化疗和放疗相关心肌损伤的识别。
Radial arterial waves for chemotherapy- and radiotherapy-related myocardial damage identification in patients with breast cancer.
发表日期:2023
作者:
Chia-Ying Lee, Daniela Yunchin Yen, Mark C Hou, Ying-Ling Chen, Rong-Jen Shiau
来源:
BIOMEDICINE & PHARMACOTHERAPY
摘要:
乳腺癌的化疗和放疗会引起副作用,例如心血管变化,可以通过超声心动图进行监测。然而,我们总是鼓励更方便的方法。用于检测心血管变化的桡动脉波可用于辅助确认心血管变化。这项回顾性研究旨在分析乳腺癌患者的桡动脉脉搏波的频域和时域,以了解其识别心血管变化的有效性.根据彰化基督教医院的脉象记录筛选乳腺癌患者,分为治疗组和缓解组。数据解链后,对乳腺癌治疗组和缓解组的脉搏数据进行分析,包括连续四个月内连续四次脉象诊断记录的参数平均值,以检验乳腺癌治疗组和缓解组之间脉搏波的差异。两组。此外,使用变异系数比较两组的脉搏波稳定性。治疗组19名患者和缓解组40名患者的脉搏波数据比较显示45个时域参数和50个频域参数。 D3、ND3、NA1、NT1是差异显着(p < 0.05)的四个参数,均与心功能相关,且主要与心输出量和外周阻力相关,表明治疗期间患者心功能较差。两组之间的数据分散程度没有差异。乳腺癌治疗引起的心血管副作用主要表现在脉搏波时域。©作者。
Chemotherapy and radiation therapy for breast cancer cause side effects, such as cardiovascular changes, which can be monitored with echocardiography. However, more convenient methods are always encouraged. Radial arterial waves that are used to detect cardiovascular changes can be used to assist in confirming cardiovascular changes.This retrospective study aimed to analyze the frequency and time domains of the radial artery pulse wave in patients with breast cancer to understand its effectiveness in identifying cardiovascular changes.Patients with breast cancer were screened from the pulse examination records in Changhua Christian Hospital and divided into the treatment and remission groups. After unlinking the data, the pulse data were analyzed for the breast cancer treatment and remission group, including the average value of the parameters of four consecutive pulse diagnosis records in four consecutive months to test the difference in pulse waves due to breast cancer treatment between the two groups. Additionally, the pulse wave stability of the two groups was compared using the coefficient of variation.The comparison of the pulse wave data between 19 patients in the treatment group and 40 patients in the remission group revealed 45 parameters in time and 50 in frequency domains. D3, ND3, NA1, and NT1 are the four parameters with significant differences (p < 0.05), which are all related to heart function, and mainly related to cardiac output and peripheral resistance, indicating that patients in the treatment period have poor heart function. No difference was found in the degree of data dispersion between the two groups. Cardiovascular side effects caused by breast cancer treatment can mainly be shown in the pulse wave time domain.© the Author(s).