背景前列腺癌（PC）通常在初次切除后发生转移，手术切除多发性肺转移瘤后的长期生存很少见。我们介绍了一位外科医生的案例，他在克服了 PC 多发性肺转移的反复手术挑战后表现出长期生存。病例报告 二十六年前，一名 62 岁的男子最初报告排尿时感到不适。前列腺检查显示前列腺特异性抗原（PSA）水平轻度升高。六个月后，诊断为PC，并进行了根治性前列腺切除术，显示为中分化腺癌，但无血管浸润。术后9年，右肺发现3个10毫米结节。然后，通过肺楔形切除术进行手术活检，发现转移性 PC，因此计划进行包括所有结节在内的右下肺叶切除术。尽管术后使用黄体生成素释放激素激动剂维持低PSA水平3年，但在对侧左肺中观察到其他新​​的局限性转移，需要更多的部分左肺切除手术。六年后，发现第三处肺转移，肿瘤大小和 PSA 水平轻度增加，患者在初次 PC 干预后 26 年死亡，原因是跌倒造成骨压缩性骨折，营养不良 1 年。 ，而不是由于 PC 的进步。结论 对于生长缓慢的转移性肺 PC，反复手术切除是一种替代治疗方法，可在本病例 26 年内实现良好的生存率和良好的生活质量。

BACKGROUND Prostate cancer (PC) often metastasizes after primary resection, and long-term survival following surgical removal of multiple pulmonary metastases is rare. We present a case of a surgeon who demonstrated long-term survival after overcoming repeated surgical challenges for multiple pulmonary metastases from PC. CASE REPORT Twenty-six years ago, a 62-year-old man initially reported discomfort during urination. A prostate examination revealed mildly elevated prostate-specific antigen (PSA) levels. Six months later, PC was diagnosed, and a radical prostatectomy was performed, revealing moderately differentiated adenocarcinoma but no vessel infiltration. At 9 years after the operation, three 10-mm nodules were detected in the right lung. Then, surgical biopsy by wedge pulmonary resection revealed metastatic PC, and therefore, right lower lobectomy including all nodules was planned. Although postoperative maintenance with luteinizing hormone-releasing hormone agonists kept the low PSA levels for 3 years, other newly limited metastases were observed in the opposite left lung, necessitating more surgeries of partial left lung resection. Six years later, a third lung metastasis was detected, as well as mild increases in the tumor size and PSA level, and the patient died 26 years after the initial PC intervention because of malnutrition for 1 year after sustaining bone compression fractures due to a fall, and not due to PC progression. CONCLUSIONS Repeated surgical resections for slow-growing metastatic pulmonary PC was an alternative treatment that facilitated favorable survival and a good quality of life for 26 years in the present case.